New hope for advanced breast cancer: experimental drug combo enters final testing phase
NCT ID NCT05909397
Summary
This study is testing whether a new drug called vepdegestrant, when combined with palbociclib, works better than the current standard treatment (letrozole plus palbociclib) for advanced breast cancer. It's for adults with a specific type of breast cancer (estrogen receptor positive, HER2 negative) who haven't yet received any treatment for their advanced disease. The trial will compare how long patients live without their cancer getting worse and monitor side effects of both treatment approaches.
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Contacts and locations
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Locations
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Aichi Cancer Center Hospital
Nagoya, Aichi-ken, 464-8681, Japan
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BRCR Global
Plantation, Florida, 33322, United States
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BRCR Medical Center Inc
Plantation, Florida, 33322, United States
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Barwon Health
Geelong, Victoria, 3220, Australia
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Cancer Hospital Chinese Academy of Medical Science
Beijing, Beijing Municipality, 100021, China
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Cancer Research SA
Adelaide, South Australia, 5000, Australia
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Centro Gaucho Integrado De Oncologia, Hematologia, Ensino E Pesquisa
Porto Alegre, Rio Grande do Sul, 90110-270, Brazil
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Centro de Pesquisa Clínica - Área Administrativa
Porto Alegre, Rio Grande do Sul, 90850-170, Brazil
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Complejo Hospitalario de Jaén
Jaén, JAÉN, 23007, Spain
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Debreceni Egyetem Klinikai Kozpont
Debrecen, 04032, Hungary
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Fakultna nemocnica s poliklinikou J.A. Reimana Presov
Prešov, 080 01, Slovakia
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Fondazione IRCCS San Gerardo dei Tintori
Monza, Lombardy, 20900, Italy
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Hospital Clinico San Carlos
Madrid, 28040, Spain
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Hospital Mae de Deus
Porto Alegre, Rio Grande do Sul, 90880-480, Brazil
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Hospital Santa Rita de Cassia
Vitória, Espírito Santo, 29043-260, Brazil
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Hospital Universitari Dexeus
Barcelona, Catalunya [cataluña], 08028, Spain
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Hospital Universitario Virgen de la Victoria
Málaga, Málaga, 29010, Spain
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Hospital Unviersitario Virgen Nieves
Granada, 18012, Spain
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Hubei Cancer Hospital
Wuhan, Hubei, 430079, China
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IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"
Meldola, Emilia-Romagna, 47014, Italy
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Institut Català d'Oncologia (ICO) - Badalona
Badalona, Barcelona [barcelona], 08916, Spain
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Istituto Nazionale Tumori IRCCS Fondazione Pascale
Napoli, Campania, 80131, Italy
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National Cancer Center Hospital
Chuo-ku, Tokyo, 104-0045, Japan
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National Cancer Center Hospital East
Kashiwa, Chiba, 277-8577, Japan
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Nemocnica na okraji mesta n o
Partizánske, 95801, Slovakia
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Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, 510060, China
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The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, 710061, China
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Tumor Zentrum Aarau
Aarau, Canton of Aargau, 5000, Switzerland
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Virginia Oncology Associates
Norfolk, Virginia, 23502, United States
Conditions
Explore the condition pages connected to this study.