First patients to receive new 'T-Cell Redirecting' drug for rare blood cancers

NCT ID NCT06150157

Summary

This is the first study in people to test a new drug called JNJ-88549968 for blood cancers with a specific genetic change (CALR mutation). The main goals are to find a safe dose and understand how the body handles the drug. The drug works by guiding a patient's own immune cells to attack the cancer cells.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH LYON SUD - Hematology

    RECRUITING

    Pierre-Bénite, 69495, France

  • Carmel Medical Center

    RECRUITING

    Haifa, 3436212, Israel

  • Charite Campus Benjamin Franklin

    RECRUITING

    Berlin, 12203, Germany

  • Churchill Hospital

    RECRUITING

    Oxford, OX3 7LE, United Kingdom

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

  • Guy's and St Thomas' Hospital

    RECRUITING

    London, SE1 9RT, United Kingdom

  • Hadassah University Hospita Ein Kerem

    RECRUITING

    Jerusalem, 9112001, Israel

  • Hopital Saint Louis

    RECRUITING

    Paris, 75475, France

  • Hosp. Clinico Univ. de Valencia

    RECRUITING

    Valencia, 46010, Spain

  • Hosp. Univ. Germans Trias I Pujol

    RECRUITING

    Badalona, 08916, Spain

  • Jewish General Hospital

    RECRUITING

    Montreal, Quebec, H3T 1E2, Canada

  • Levine Cancer Institute

    RECRUITING

    Charlotte, North Carolina, 28204, United States

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Med. Universitatsklinik Essen

    RECRUITING

    Essen, 45147, Germany

  • Medizinische Hochschule Hannover

    RECRUITING

    Hanover, 30625, Germany

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • Moffit Cancer center

    RECRUITING

    Tampa, Florida, 33612, United States

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10467, United States

  • Policlinico Sant'Orsola Malpighi

    RECRUITING

    Bologna, 40138, Italy

  • Policlinico di Milano

    RECRUITING

    Milan, 21022, Italy

  • Princess Margaret Cancer Centre University Health Network

    RECRUITING

    Toronto, Ontario, M5G 1Z5, Canada

  • Sarah Cannon Cancer Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Sheba Medical Center

    RECRUITING

    Ramat Gan, 5266202, Israel

  • Tel Aviv Sourasky Medical Center

    RECRUITING

    Tel Aviv, 64239, Israel

  • UCHealth Cancer Care Anschutz Medical Campus University of Colorado Cancer Center

    RECRUITING

    Aurora, Colorado, 80045, United States

  • Universitaetsklinikum Heidelberg

    RECRUITING

    Heidelberg, 69120, Germany

  • Universitaetsklinikum Regensburg

    RECRUITING

    Regensburg, 93053, Germany

  • Universitaetsklinikum der RWTH Aachen

    RECRUITING

    Aachen, 52074, Germany

  • University College London Hospitals Nhs Foundation Trust

    RECRUITING

    London, NW1 2PG, United Kingdom

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.