New balloon aims to keep leg arteries open, prevent amputations

NCT ID NCT05132361

Summary

This study is testing a new type of balloon coated with a drug (sirolimus) to see if it works better than a standard balloon at keeping leg arteries open. It involves 300 people with narrowed or blocked arteries in their upper leg, which can cause pain and difficulty walking. The main goal is to see if the drug-coated balloon keeps the artery open longer and reduces the need for repeat procedures or major amputations.

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Contacts and locations

Locations

  • Advocate Lutheran General Hospital

    Park Ridge, Illinois, 60068, United States

  • Alexianer Klinikum Hochsauerland

    Arnsberg, 59759, Germany

  • Arkansas Heart Hospital

    Little Rock, Arkansas, 72211, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Cardiovascular Consultants of South Georgia

    Thomasville, Georgia, 31792, United States

  • Cardiovascular Institute of the South

    Gray, Louisiana, 70359, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • ClinRé

    Thornton, Colorado, 80023, United States

  • El Paso Cardiology

    El Paso, Texas, 79902, United States

  • Emory University Hospital

    Atlanta, Georgia, 30322, United States

  • First Coast Cardiovascular Institute

    Jacksonville, Florida, 32218, United States

  • Guardian Research Organization, LLC

    Winter Park, Florida, 32792, United States

  • Heart Care Centers Research Foundation

    Palos Park, Illinois, 60464, United States

  • Heart Hospital Baylor Plano

    Plano, Texas, 75093, United States

  • Holy Name Medical Center

    Teaneck, New Jersey, 07666, United States

  • James J. Peters VA Medical Center

    The Bronx, New York, 10468, United States

  • Krankenhaus Buchholz

    Buchholz, 21244, Germany

  • Manatee Memorial Hospital

    Bradenton, Florida, 34205, United States

  • MedStar Health Research Institute

    Hyattsville, Maryland, 20782, United States

  • Memorial Healthcare System

    Hollywood, Florida, 33021, United States

  • Mercy Hospital

    St Louis, Missouri, 63128, United States

  • Miriam Hospital

    Providence, Rhode Island, 02906, United States

  • Mission Cardiovascular Research Institute

    Fremont, California, 94538, United States

  • NC Heart and Vascular Research, LLC

    Raleigh, North Carolina, 27607, United States

  • Palm Vascular Centers

    Miami Beach, Florida, 33140, United States

  • Queen Mary Hospital

    Hong Kong, Pok Fu Lam, Hong Kong

  • RoMed Klinikum Rosenheim

    Rosenheim, 83022, Germany

  • Sana Kliniken Oberfranken Coburg

    Coburg, 96450, Germany

  • St. Helena Hospital

    St. Helena, California, 94558, United States

  • Tennessee Center for Clinical Trials

    Tullahoma, Tennessee, 37388, United States

  • Texas Cardiac and Vascular Institute San Antonio

    San Antonio, Texas, 78229, United States

  • The Cardiac and Vascular Institute Research Foundation

    Gainesville, Florida, 32605, United States

  • The Chinese University of Hong Kong

    Shatin, Hong Kong

  • University Clinic Tübingen

    Tübingen, 72076, Germany

  • Universitäts-Herzzentrum Freiburg - Bad Krozingen

    Bad Krozingen, 79189, Germany

  • Universitätsklinikum Graz

    Graz, A-8036, Austria

  • Universitätsklinikum Leipzig

    Leipzig, 04103, Germany

  • Vascular Care Group

    Darien, Connecticut, 06820, United States

Conditions

Explore the condition pages connected to this study.