New hope for Hard-to-Treat leukemia: drug cocktail shows promise

NCT ID NCT05442216

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 24 times

Summary

This study tests a new combination of three drugs (tagraxofusp, azacitidine, and venetoclax) for people with a type of acute myeloid leukemia (AML) that has come back or not responded to previous treatment. The goal is to see if this combination can help achieve remission. About 53 adults will take part, receiving the drugs in 28-day cycles.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AdventHealth Orlando

    RECRUITING

    Orlando, Florida, 32803, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • Lifespan Health System Rhode Island Hospital

    RECRUITING

    Providence, Rhode Island, 46278, United States

    Contact Email: •••••@•••••

    Contact

  • Penn Medicine Abramson Cancer Center

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact Email: •••••@•••••

  • Roswell Park Cancer Institute

    RECRUITING

    Buffalo, New York, 14263, United States

    Contact Email: •••••@•••••

    Contact

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.