Triple-Threat attack on tough blood cancers begins human testing

NCT ID NCT05010122

Summary

This study is testing a new combination of three oral drugs (ASTX727, venetoclax, and gilteritinib) for adults with specific types of acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) that have a genetic change called an FLT3 mutation. The first part aims to find the safest dose, and the second part will see how well the combination works to control the disease. The goal is to see if this approach helps patients who are newly diagnosed, or whose cancer has returned or not responded to prior treatment.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.