New Triple-Threat treatment tested for aggressive blood cancers

NCT ID NCT03862157

Summary

This study is testing a combination of three drugs—azacitidine, venetoclax, and pevonedistat—for adults newly diagnosed with certain high-risk blood cancers. These include acute myeloid leukemia (AML) that developed from other blood disorders or prior cancer treatment, as well as high-risk myelodysplastic syndrome (MDS). The first part of the study aims to find the safest and most effective dose of venetoclax when used with the other two drugs. The second part will see how well the combination works to control the disease.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.