Scientists test new pill to boost power of leukemia chemotherapy

NCT ID NCT04190550

Summary

This early-stage study is testing a new oral drug called navtemadlin (KRT-232) in combination with standard chemotherapy for adults newly diagnosed with a fast-growing blood cancer called acute myeloid leukemia (AML). The main goals are to find the safest and most effective dose of the new combination and to understand its side effects. Researchers hope adding navtemadlin, which targets a specific protein in cancer cells, will help control the leukemia better than chemotherapy alone.

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Contacts and locations

Locations

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    New York, New York, 10016, United States

  • Los Angeles General Medical Center

    Los Angeles, California, 90033, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • University of Maryland/Greenebaum Cancer Center

    Baltimore, Maryland, 21201, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

Conditions

Explore the condition pages connected to this study.