New hope for older adults battling aggressive blood cancer

NCT ID NCT04994717

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new treatment approach works better than standard chemotherapy for older adults with a fast-growing blood cancer called acute lymphoblastic leukemia (ALL). The new approach combines a targeted immunotherapy drug (blinatumomab) with lower-intensity chemotherapy. Researchers will compare how long patients live without their cancer returning and their overall survival between the two treatment groups.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AZ Delta Campus Rumbeke
RECRUITING

Roeselare, 8800, Belgium
AZ Sint-Jan Brugge-Oostende AV
RECRUITING

Bruges, 8000, Belgium
Aalborg Universitetshospital
RECRUITING

Aalborg, 9000, Denmark
Aarhus Universitetshospital
RECRUITING

Aarhus N, 8200, Denmark
Adventist Health System/Sunbelt, Inc d/b/a AdventHealth Orlando
TERMINATED

Orlando, Florida, 32804, United States
Akita University Hospital
RECRUITING

Akita, Akita, 010-8543, Japan
Ankara Bilkent Sehir Hastanesi
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Arthur J E Child Comprehensive Cancer Centre
RECRUITING

Calgary, Alberta, T2N 5G2, Canada
Attiko General University Hospital
RECRUITING

Athens, 12462, Greece
Austin Health, Austin Hospital
RECRUITING

Heidelberg, Victoria, 3084, Australia
Azienda Ospedaliera Policlinico Umberto I
RECRUITING

Roma, 00161, Italy
Azienda Ospedaliera Universitaria Consorziale Policlinico di Bari
TERMINATED

Bari, 70124, Italy
Azienda Ospedaliera Universitaria Integrata di Verona Ospedale G B Rossi Borgo Roma
TERMINATED

Verona, 37134, Italy
Azienda Ospedaliera di Perugia Ospedale Santa Maria della Misericordia
RECRUITING

Perugia, 06156, Italy
Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli
RECRUITING

Naples, 80131, Italy
Azienda Ospedaliero Universitaria Citta della Salute e della Scienza di Torino
RECRUITING

Torino, 10126, Italy
Azienda Socio Sanitaria Territoriale Papa Giovanni xxiii
RECRUITING

Bergamo, 24127, Italy
Azienda Unita Sanitaria Locale LE Presidio Ospedaliero Vito Fazzi Polo Oncologico Giovanni Paolo II
TERMINATED

Lecce, 73100, Italy
Azienda Unita Sanitaria Locale Pescara Ospedale Civile Santo Spirito
RECRUITING

Pescara, 65124, Italy
Azienda Unità Locale Socio Sanitaria 3 Ospedale Dell Angelo
RECRUITING

Mestre (VE), 30174, Italy
Bagcilar Medipol Mega Universite Hastanesi
RECRUITING

Istanbul, 34214, Turkey (Türkiye)
Boca Clinical Trials Mexico SC
TERMINATED

Mexico City, Mexico City, 01120, Mexico
CEMTL Hopital Maisonneuve Rosemont
RECRUITING

Montreal, Quebec, H1T 2M4, Canada
Canberra Hospital
RECRUITING

Garran, Australian Capital Territory, 2605, Australia
Cancer Care Manitoba
RECRUITING

Winnipeg, Manitoba, R3H 0V9, Canada
Centre Hospitalier Regional Universitaire de Lille - Hopital Claude Huriez
RECRUITING

Lille, 59000, France
Centre Hospitalier Universitaire Archet 2
RECRUITING

Nice, 06202, France
Centre Hospitalier Universitaire de Bordeaux - Hopital Haut Leveque
RECRUITING

Pessac, 33604, France
Centre Hospitalier Universitaire de Dijon - Hopital du Bocage
RECRUITING

Dijon, 21000, France
Centre Hospitalier Universitaire de Liege - Sart Tilman
RECRUITING

Liège, 4000, Belgium
Centre Hospitalier Universitaire de Nancy - Hopital de Brabois
RECRUITING

Vandœuvre-lès-Nancy, 54511, France
Centre Hospitalier Universitaire de Nantes - Hopital Hotel Dieu
RECRUITING

Nantes, 44000, France
Centre Hospitalier Universitaire de Rennes
RECRUITING

Rennes, 35000, France
Centre Hospitalier Universitaire-Universite Catholique de Louvain Namur-Site Godinne
RECRUITING

Yvoir, 5530, Belgium
Centre Hospitalier de Versailles - Hopital Andre Mignot
RECRUITING

Le Chesnay, 78157, France
Centro Oncologico Internacional
RECRUITING

Mexico City, Mexico City, 01330, Mexico
Charite - Universitaetsmedizin Berlin, Campus Benjamin Franklin
COMPLETED

Berlin, 12203, Germany
China Medical University Hospital
RECRUITING

Taichung, 40458, Taiwan
Chonnam National University Hwasun Hospital
RECRUITING

Hwasun, 58128, South Korea
Chungnam National University Hospital
RECRUITING

Daejeon, 35015, South Korea
City of Hope National Medical Center
RECRUITING

Duarte, California, 91010, United States
Cleveland Clinic Foundation
TERMINATED

Cleveland, Ohio, 44195, United States
Clinica Alemana de Santiago
RECRUITING

Santiago, 7650729, Chile
Complejo Asistencial Universitario de Salamanca Hospital Universitario de Salamanca
RECRUITING

Salamanca, Castille and León, 37007, Spain
Debreceni Egyetem Klinikai Kozpont
RECRUITING

Debrecen, 4032, Hungary
Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet
RECRUITING

Budapest, 1097, Hungary
Dokuz Eylul Universitesi Tip Fakultesi Hastanesi
RECRUITING

Izmir, 35340, Turkey (Türkiye)
Dong-A University Hospital
RECRUITING

Busan, 49201, South Korea
Evangelismos Hospital
RECRUITING

Athens, 10676, Greece
Fakultni nemocnice Brno
RECRUITING

Brno, 625 00, Czechia
Fakultni nemocnice Hradec Kralove
RECRUITING

Hradec Králové, 500 05, Czechia
Fiona Stanley Hospital
RECRUITING

Murdoch, Western Australia, 6150, Australia
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico
RECRUITING

Milan, 20122, Italy
Fukushima Medical University Hospital
RECRUITING

Fukushima, Fukushima, 960-1295, Japan
Fundacao Amaral Carvalho
RECRUITING

Jaú, São Paulo, 17210-120, Brazil
Fundacion Arturo Lopez Perez
RECRUITING

Santiago, 7500921, Chile
General Hospital of Thessaloniki Georgios Papanikolaou
RECRUITING

Thessaloniki, 57010, Greece
Gunma Saiseikai Maebashi Hospital
RECRUITING

Maebashi, Gunma, 371-0821, Japan
Hacettepe Universitesi Tip Fakultesi Hastanesi
RECRUITING

Ankara, 06100, Turkey (Türkiye)
Hamilton Health Sciences - Juravinski Hospital and Cancer Centre
RECRUITING

Hamilton, Ontario, L8V 5C2, Canada
Hanusch Krankenhaus
COMPLETED

Vienna, 1140, Austria
Helsinki University Hospital
RECRUITING

Helsinki, 00029, Finland
Hematologica Alta Especialidad
RECRUITING

Huixquilucan, 52787, Mexico
Hemorio
RECRUITING

Rio de Janeiro, 22640-000, Brazil
Heves Varmegyei Markhot Ferenc Oktatokorhaz es Rendelointezet
RECRUITING

Eger, 3300, Hungary
Hopital Henri Mondor
RECRUITING

Créteil, 94010, France
Hopital Lyon Sud
RECRUITING

Pierre-Bénite, 69645, France
Hopital Saint Antoine
RECRUITING

Paris, 75012, France
Hopital Saint Louis
RECRUITING

Paris, 75010, France
Hosp Clin Fac Med Ribeirao Preto Usp
RECRUITING

Ribeirão Preto, São Paulo, 14048-900, Brazil
Hospital Universitari Vall d Hebron
RECRUITING

Barcelona, Catalonia, 08035, Spain
Hospital Universitari i Politecnic La Fe
RECRUITING

Valencia, Valencia, 46026, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Dr Jose Eleuterio Gonzalez
RECRUITING

Monterrey, Nuevo León, 64460, Mexico
Hospital Universitario Marques de Valdecilla
RECRUITING

Santander, Cantabria, 39008, Spain
Hospital Universitario Reina Sofia
RECRUITING

Córdoba, Andalusia, 14004, Spain
Hospital Universitario Virgen del Rocio
TERMINATED

Seville, Andalusia, 41013, Spain
Hospital das Clinicas da Universidade Federal de Goias
RECRUITING

Goiânia, Goiás, 74605-020, Brazil
Hospital de Base de Sao Jose do Rio Preto
RECRUITING

São Jose Do Rio Preto, São Paulo, 15090-000, Brazil
Hospital de Clinicas de Porto Alegre
RECRUITING

Porto Alegre, Rio Grande do Sul, 90035-003, Brazil
IRCCS Azienda Ospedaliero Universitaria di Bologna Policlinico di Sant Orsola
RECRUITING

Bologna, 40138, Italy
Igesd Instituto de Gestao Estrategica da Saude do Distrito Federal
RECRUITING

Brasília, Federal District, 70335-902, Brazil
Inmunocel
RECRUITING

Santiago, 7580206, Chile
Inselspital Bern
ACTIVE_NOT_RECRUITING

Bern, 3010, Switzerland
Institut Catala d Oncologia Badalona Hospital Universitari Germans Trias i Pujol
RECRUITING

Badalona, Catalonia, 08916, Spain
Institut Catala d Oncologia Hospitalet Hospital Duran i Reynals
RECRUITING

L'Hospitalet de Llobregat, Catalonia, 08908, Spain
Institut Jules Bordet
RECRUITING

Anderlecht, 1070, Belgium
Institut Paoli Calmettes
RECRUITING

Marseille, 13009, France
Institut Universitaire du Cancer Toulouse Oncopole
RECRUITING

Toulouse, 31059, France
Instituto Cancer Sao Paulo Icesp
RECRUITING

São Paulo, 01246-000, Brazil
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
RECRUITING

Mexico City, 14080, Mexico
Instituto Portugues de Oncologia de Lisboa Francisco Gentil, EPE
RECRUITING

Lisbon, 1099-023, Portugal
Instituto Portugues de Oncologia do Porto Francisco Gentil, EPE
RECRUITING

Porto, 4200-072, Portugal
Institutul Clinic Fundeni
RECRUITING

Bucharest, 022328, Romania
Institutul Oncologic Prof Dr Ion Chiricuta
RECRUITING

Cluj-Napoca, 400015, Romania
Institutul Regional de Oncologie Iasi
RECRUITING

Iași, 700483, Romania
Jessa Ziekenhuis - Campus Virga Jesse
RECRUITING

Hasselt, 3500, Belgium
Jichi Medical University Hospital
RECRUITING

Shimotsuke-shi, Tochigi, 329-0498, Japan
Kanazawa University Hospital
RECRUITING

Kanazawa, Ishikawa-ken, 920-8641, Japan
Kindai University Hospital
RECRUITING

Sakai-shi, Osaka, 590-0197, Japan
Kings College Hospital
RECRUITING

London, SE5 9RS, United Kingdom
Klinikum der LMU Muenchen
COMPLETED

München, 81377, Germany
Kobe City Medical Center General Hospital
RECRUITING

Kobe, Hyōgo, 650-0047, Japan
Kurume University Hospital
RECRUITING

Kurume-shi, Fukuoka, 830-0011, Japan
Kyoto University Hospital
RECRUITING

Kyoto, Kyoto, 606-8507, Japan
Kyushu University Hospital
RECRUITING

Fukuoka, Fukuoka, 812-8582, Japan
Laiko General Hospital of Athens
RECRUITING

Athens, 11527, Greece
Linkou Chang Gung Memorial Hospital of Chang Gung Medical Foundation
RECRUITING

Taoyuan District, 33305, Taiwan
Liverpool Hospital
RECRUITING

Liverpool, New South Wales, 2170, Australia
Medizinische Universitaet Graz
RECRUITING

Graz, 8036, Austria
Medizinische Universitaet Innsbruck
COMPLETED

Innsbruck, 6020, Austria
Memorial Antalya Hastanesi
RECRUITING

Antalya, 07025, Turkey (Türkiye)
Monash Medical Centre
COMPLETED

Clayton, Victoria, 3168, Australia
Nagasaki University Hospital
RECRUITING

Nagasaki, Nagasaki, 852-8501, Japan
Nagoya University Hospital
RECRUITING

Nagoya, Aichi-ken, 466-8560, Japan
Narodny onkologicky ustav
RECRUITING

Bratislava, 833 10, Slovakia
National Cheng Kung University Hospital
RECRUITING

Tainan, 70403, Taiwan
National Hospital Organization Okayama Medical Center
RECRUITING

Okayama, Okayama-ken, 701-1192, Japan
National Taiwan University Hospital
RECRUITING

Taipei, 10002, Taiwan
Nihon University Itabashi Hospital
RECRUITING

Itabashi-ku, Tokyo, 173-8610, Japan
North Estonia Medical Centre
RECRUITING

Tallinn, 13 419, Estonia
Odense Universitetshospital
RECRUITING

Odense, 5000, Denmark
Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi
RECRUITING

Samsun, 55139, Turkey (Türkiye)
Ordensklinikum Linz Elisabethinen
COMPLETED

Linz, 4020, Austria
Osaka Metropolitan University Hospital
RECRUITING

Osaka, Osaka, 545-8586, Japan
Ospedale Policlinico San Martino IRCCS
RECRUITING

Genova, 16132, Italy
Peter MacCallum Cancer Centre
RECRUITING

Melbourne, Victoria, 3000, Australia
Princess Alexandra Hospital
RECRUITING

Woolloongabba, Queensland, 4102, Australia
Princess Margaret Cancer Centre
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Princess Margaret Hospital
RECRUITING

Kowloon, Hong Kong
Pusan National University Hospital
RECRUITING

Busan, 49241, South Korea
Queen Elizabeth II, Health Sciences Centre
RECRUITING

Halifax, Nova Scotia, B3H 1V8, Canada
Queen Mary Hospital, The University of Hong Kong
RECRUITING

Hong Kong, Hong Kong
Rabin Medical Center - Beilinson Hospital
RECRUITING

Petah Tikva, 4941492, Israel
Rambam Medical Center
RECRUITING

Haifa, 3109601, Israel
Rigshospitalet
RECRUITING

København Ø, 2100, Denmark
Royal Adelaide Hospital
RECRUITING

Adelaide, South Australia, 5000, Australia
Royal Brisbane and Womens Hospital
RECRUITING

Herston, Queensland, 4029, Australia
Royal North Shore Hospital
RECRUITING

St Leonards, New South Wales, 2065, Australia
Royal Prince Alfred Hospital
RECRUITING

Camperdown, New South Wales, 2050, Australia
Sahlgrenska Universitetssjukhuset
RECRUITING

Gothenburg, 413 45, Sweden
Saint Francis Hospital, Inc
COMPLETED

Greenville, South Carolina, 29607, United States
Sapporo Hokuyu Hospital
RECRUITING

Sapporo, Hokkaido, 003-0006, Japan
Semmelweis Egyetem
RECRUITING

Budapest, 1088, Hungary
Seoul National University Hospital
RECRUITING

Seoul, 03080, South Korea
Severance Hospital Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
Shaare Zedek Medical Center
RECRUITING

Jerusalem, 9103102, Israel
Specialized Hospital for Active Treatment of Hematology Diseases EAD
TERMINATED

Sofia, 1797, Bulgaria
Spitalul Clinic Judetean de Urgenta Sibiu
RECRUITING

Sibiu, 550245, Romania
Spitalul Clinic Municipal Filantropia Craiova
RECRUITING

Craiova, 200143, Romania
Spitalul Universitar de Urgenta Bucuresti
RECRUITING

Bucharest, 050098, Romania
Szabolcs-Szatmar-Bereg Varmegyei Oktatokorhaz Nyiregyhazi Josa Andras Tagkorhaz
RECRUITING

Nyíregyháza, 4400, Hungary
Taichung Veterans General Hospital
RECRUITING

Taichung, 40705, Taiwan
Tartu University Hospital
RECRUITING

Tartu, 51014, Estonia
Tesshokai Kameda General Hospital
RECRUITING

Kamogawa-shi, Chiba, 296-8602, Japan
The Alfred Hospital
RECRUITING

Melbourne, Victoria, 3004, Australia
The Catholic University of Korea Seoul St Marys Hospital
RECRUITING

Seoul, 06591, South Korea
The Ottawa Hospital Cancer Centre
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada
Tohoku University Hospital
RECRUITING

Sendai, Miyagi, 980-8574, Japan
Tokai University Hospital
RECRUITING

Isehara-shi, Kanagawa, 259-1193, Japan
Tokyo Metropolitan Komagome Hospital
RECRUITING

Bunkyo-ku, Tokyo, 113-8677, Japan
Tuen Mun Hospital
RECRUITING

New Territories, Hong Kong
Turku University Hospital
RECRUITING

Turku, 20521, Finland
Unidade Local de Saude de Coimbra, EPE
RECRUITING

Coimbra, 3004-561, Portugal
Unidade Local de Saude de Santa Maria, EPE - Hospital de Santa Maria
RECRUITING

Lisbon, 1649-035, Portugal
Unidade Local de Saude de Sao Jose, EPE - Hospital de Santo Antonio dos Capuchos
RECRUITING

Lisbon, 1169-050, Portugal
Universitaetsklinikum Augsburg
COMPLETED

Augsburg, 86156, Germany
Universitaetsklinikum Dresden
COMPLETED

Dresden, 01307, Germany
Universitaetsklinikum Duesseldorf
COMPLETED

Düsseldorf, 40225, Germany
Universitaetsklinikum Heidelberg
COMPLETED

Heidelberg, 69120, Germany
Universitaetsklinikum Jena
COMPLETED

Jena, 07747, Germany
Universitaetsklinikum Schleswig-Holstein - Kiel
COMPLETED

Kiel, 24105, Germany
Universitair Medisch Centrum Groningen
ACTIVE_NOT_RECRUITING

Groningen, 9713 GZ, Netherlands
Universitair Ziekenhuis Antwerpen
RECRUITING

Edegem, 2650, Belgium
Universitair Ziekenhuis Gent
RECRUITING

Ghent, 9000, Belgium
Universite Catholique de Louvain Cliniques Universitaires Saint Luc
TERMINATED

Brussels, 1200, Belgium
University College London
COMPLETED

London, NW1 2PG, United Kingdom
University Hospital of Heraklion
RECRUITING

Heraklion, 71500, Greece
University Hospital of Ioannina
RECRUITING

Ioannina, 45500, Greece
University Hospital of Larissa
RECRUITING

Larissa, 41110, Greece
University Hospital of Patras
RECRUITING

Pátrai, 26504, Greece
University Multiprofile Hospital for Active Treatment Sveti Georgi EAD
RECRUITING

Plovdiv, 40002, Bulgaria
University of California Irvine
RECRUITING

Orange, California, 92868-3201, United States
University of California San Francisco
RECRUITING

San Francisco, California, 94143, United States
University of Fukui Hospital
RECRUITING

Yoshida-gun, Fukui, 910-1193, Japan
University of Texas MD Anderson Cancer Center
COMPLETED

Houston, Texas, 77030, United States
Univerzitna nemocnica Bratislava, Nemocnica sv Cyrila a Metoda
RECRUITING

Bratislava, 851 07, Slovakia
Ustav hematologie a krevni transfuze
RECRUITING

Prague, 128 20, Czechia
Vancouver General Hospital, Gordon and Leslie Diamond Health Care Centre
RECRUITING

Vancouver, British Columbia, V5Z 1M9, Canada
Westmead Hospital
TERMINATED

Westmead, New South Wales, 2145, Australia
Yamagata University Hospital
RECRUITING

Yamagata, Yamagata, 990-9585, Japan
Yokohama City University Medical Center
RECRUITING

Yokohama, Kanagawa, 232-0024, Japan

Conditions

Explore the condition pages connected to this study.

NEWLY DIAGNOSED PHILADELPHIA (PH)-NEGATIVE B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)