Electric pulses to the head: new device aims to stop cluster headaches
NCT ID NCT07113470
First seen Jun 24, 2026 · Last updated Jul 17, 2026 · Updated 4 times
Summary
This small study tests an implanted device that sends mild electrical pulses to nerves in the head and neck to prevent chronic cluster headaches. Ten adults who did not get better with the drug verapamil will receive the stimulator. Researchers will check how safe it is and whether it reduces headache attacks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- implanted nerve stimulator (PRIMUS system)
- What this could lead to
- If it works, this could offer a new drug-free option for preventing chronic cluster headaches in people who don't get relief from standard medications.
- What could go wrong
- This is a very small early study with only 10 people and no placebo group, so results may not apply broadly. The device requires surgery and carries risks like infection or nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
LUMC Leids Universitair Medisch Centrum
RECRUITINGLeiden, Netherlands
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Other studies related to the condition(s) this trial covers.