New nerve block combo may cut opioid use after heart surgery

NCT ID NCT07658521

ENROLLING_BY_INVITATION Symptom relief Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding two ultrasound-guided nerve blocks to standard pain relief can lower opioid use and pain after coronary artery bypass grafting. 88 adults having elective bypass surgery will be randomly assigned to receive either the nerve blocks plus standard medications or standard medications alone. Pain scores, opioid use, and recovery milestones will be tracked for 48 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bupivacaine
What this could lead to: If successful, this approach could reduce reliance on opioid painkillers and improve recovery after heart surgery.
What could go wrong: This is a small, early-stage trial (88 participants) testing a procedure, not a new drug. The nerve blocks may not significantly reduce pain or opioid use, and there are risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE PAIN FOLLOWING CORONARY ARTERY BYPASS GRAFTING (CABG)

Contacts and locations

Locations

Ain Shams University Hospitals

Cairo, Cairo Governorate, 1181, Egypt

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