Gene therapy injection could ease chronic bladder pain

NCT ID NCT07391306

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a gene therapy called Neovasculgen for people with painful bladder syndrome/interstitial cystitis, a condition causing pelvic pain and frequent urination. The treatment is injected into the bladder wall during a procedure. The goal is to reduce pain and prevent the bladder from shrinking. The trial involves 180 women aged 18-65 and compares the drug to a placebo.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Neovasculgen (a gene therapy that promotes blood vessel growth)
What this could lead to
If it works, this could offer a new treatment option for people with painful bladder syndrome, reducing pain and preventing bladder shrinkage.
What could go wrong
This is an early-to-mid stage trial with only 180 participants. The treatment involves injections into the bladder wall, which carries risks like infection or bleeding. It may not work better than placebo.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Botkin Hospital

    RECRUITING

    Moscow, Russia

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Other studies related to the condition(s) this trial covers.