Gene therapy injection could ease chronic bladder pain

NCT ID NCT07391306

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a gene therapy called Neovasculgen for people with painful bladder syndrome/interstitial cystitis, a condition causing pelvic pain and frequent urination. The treatment is injected into the bladder wall during a procedure. The goal is to reduce pain and prevent the bladder from shrinking. The trial involves 180 women aged 18-65 and compares the drug to a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Neovasculgen (a gene therapy that promotes blood vessel growth)

What this could lead to

If it works, this could offer a new treatment option for people with painful bladder syndrome, reducing pain and preventing bladder shrinkage.

What could go wrong

This is an early-to-mid stage trial with only 180 participants. The treatment involves injections into the bladder wall, which carries risks like infection or bleeding. It may not work better than placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

interstitial cystitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Botkin Hospital

    RECRUITING

    Moscow, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••