Doctors hunt for perfect moment to wake muscles after anesthesia
NCT ID NCT07524959
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how well neostigmine reverses the muscle relaxant mivacurium during foot and ankle surgery. Researchers will test 120 adults to find the best time to give neostigmine so muscles recover quickly and safely. The goal is to improve recovery from anesthesia, not to cure or treat a disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18 - 65 years old; * American Society of Anesthesiologists (ASA) physical stastus classification system: I-II; * Body mass index (BMI) 18.5 - 30 kg/m2 * Patients with normal cholinesterase levels before the operation Exclusion Criteria: * Refusal to participate in the study; * ASA classification of grade III or above; * Severe organ dysfunction, difficult airway or neurological muscle disorders; * Taking drugs that affect neuromuscular monitoring or neuromuscular conduction function; * Allergic to the test drug or having other contraindications; * Pregnant and lactating women
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beijing tongren Hospital, Capital Medical University
Beijing, Beijing Municipality, 100000, China
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