Breast cancer trial adds radiation before surgery – results incomplete

NCT ID NCT02806258

Terminated Disease control Sponsor: University Hospital, Grenoble Source: ClinicalTrials.gov ↗

First seen Jan 04, 2026 · Last updated May 10, 2026 · Updated 18 times

Summary

This study looked at women with aggressive breast cancers (triple negative or luminal B) that were too large for breast-conserving surgery at first. It compared standard chemotherapy alone versus chemotherapy plus a short course of focused radiation before surgery. The goal was to see if the combination increased the chance of no cancer remaining at surgery and allowed more women to keep their breast. The trial was terminated early, so final results are not available.

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Contacts and locations

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Locations

AP-HP Henri mondor

Paris, France
CHI Créteil

Créteil, France
CHU Avicenne

Paris, France
CHU de Grenoble

Grenoble, 38043, France
H. Hartmann Institute of Radiotherapy and Radiosurgery

Paris, France
Tenon hospital

Paris, France

Conditions

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INTERMEDIATE AND HIGH-RISK LUMINAL AND TRIPLE NEGATIVE BREAST CANCER RADIATION THERAPY, BREAST CANCER, SEQUENTIAL PARTIAL BREAST IRRADIATION