Zapping brain tumors before surgery may stop their return
NCT ID NCT01891318
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving focused radiation (radiosurgery) before surgically removing brain metastases can prevent the tumors from coming back. About 36 adults with 1 to 4 brain metastases will receive radiosurgery followed by surgery. Researchers will also monitor side effects and determine the best radiation dose.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiosurgery (focused radiation)
What this could lead to
If it works, this approach could reduce the chance of brain metastases coming back after surgery, improving local control.
What could go wrong
This is an early-phase trial with only 36 participants, so results may not apply broadly. Risks include radiation side effects and the possibility that the treatment does not prevent recurrence.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic, Case Comprehensive Cancer Center
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center
WITHDRAWNCleveland, Ohio, 44106, United States