Zapping brain tumors before surgery may stop their return
NCT ID NCT01891318
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times
Summary
This study tests whether giving focused radiation (radiosurgery) before surgically removing brain metastases can prevent the tumors from coming back. About 36 adults with 1 to 4 brain metastases will receive radiosurgery followed by surgery. Researchers will also monitor side effects and determine the best radiation dose.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiosurgery (focused radiation)
- What this could lead to
- If it works, this approach could reduce the chance of brain metastases coming back after surgery, improving local control.
- What could go wrong
- This is an early-phase trial with only 36 participants, so results may not apply broadly. Risks include radiation side effects and the possibility that the treatment does not prevent recurrence.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for TUMORS METASTATIC TO BRAIN are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Email: •••••@•••••
Locations
-
Cleveland Clinic, Case Comprehensive Cancer Center
RECRUITINGCleveland, Ohio, 44195, United States
Contact Email: •••••@•••••
-
University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center
WITHDRAWNCleveland, Ohio, 44106, United States