New immune combo aims to boost breast cancer treatment before surgery

NCT ID NCT04895761

First seen Apr 17, 2026 · Last updated May 08, 2026 · Updated 4 times

Summary

This early-phase study tests the safety of adding an immune-targeting therapy (DPX-Survivac) to standard hormone therapy (letrozole) in women with a common type of breast cancer (HR+HER2-). Some participants also receive low-dose radiation or a chemotherapy drug (cyclophosphamide). The goal is to see if these combinations are safe before surgery. Only 18 women are expected to join, and the main focus is on side effects, not yet on curing the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

Conditions

Explore the condition pages connected to this study.