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Low-dose radiation and immunotherapy show promise in shrinking lung tumors before surgery

NCT ID NCT04933903

Recruiting now Disease control Sponsor: Brown University Source: ClinicalTrials.gov ↗

First seen Jan 11, 2026 · Last updated May 13, 2026 · Updated 17 times

Summary

This study is for people with stage IB to III non-small cell lung cancer that can be removed with surgery. Before surgery, participants receive a low dose of targeted radiation along with two immunotherapy drugs (ipilimumab and nivolumab). The goal is to see if this combination can shrink or eliminate the tumor before surgery, and to check how safe the treatment is. The study involves 25 participants and uses a two-stage design to stop early if the treatment is not effective enough.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rhode Island Hospital

    RECRUITING

    Providence, Rhode Island, 02903, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.

NON-SMALL CELL LUNG CANCER