Chemo-First approach aims to save rectums in early cancer trial

NCT ID NCT03259035

Completed Disease control Sponsor: Canadian Cancer Trials Group Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested giving chemotherapy before a less invasive surgery for early rectal cancer. The goal was to see if this approach could allow patients to keep their rectum instead of needing major surgery. 58 people took part, and the treatment was considered successful if at least 65% could avoid removing the rectum.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for EARLY RECTAL ADENOCARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RECTAL CANCER

Contacts and locations

Locations

BCCA - Vancouver Cancer Centre

Vancouver, British Columbia, V5Z 4E6, Canada
CancerCare Manitoba

Winnipeg, Manitoba, R3E 0V9, Canada
Dana-Farber Cancer Institute

Boston, Massachusetts, 02115, United States
Health Sciences North

Greater Sudbury, Ontario, P3E 5J1, Canada
Kingston Health Sciences Centre

Kingston, Ontario, K7L 2V7, Canada
Ottawa Hospital Research Institute

Ottawa, Ontario, K1H 8L6, Canada
QEII Health Sciences Centre

Halifax, Nova Scotia, B3H 1V7, Canada
St. Paul's Hospital

Vancouver, British Columbia, V6Z 1Y6, Canada
The Research Institute of the McGill University

Montreal, Quebec, H4A 3J1, Canada
UC Irvine Medical Center

Orange, California, 92868, United States
Virginia Mason Medical Center

Seattle, Washington, 97101, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.