Chemo-First approach aims to save rectums in early cancer trial

NCT ID NCT03259035

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested giving chemotherapy before a less invasive surgery for early rectal cancer. The goal was to see if this approach could allow patients to keep their rectum instead of needing major surgery. 58 people took part, and the treatment was considered successful if at least 65% could avoid removing the rectum.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • BCCA - Vancouver Cancer Centre

    Vancouver, British Columbia, V5Z 4E6, Canada

  • CancerCare Manitoba

    Winnipeg, Manitoba, R3E 0V9, Canada

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Health Sciences North

    Greater Sudbury, Ontario, P3E 5J1, Canada

  • Kingston Health Sciences Centre

    Kingston, Ontario, K7L 2V7, Canada

  • Ottawa Hospital Research Institute

    Ottawa, Ontario, K1H 8L6, Canada

  • QEII Health Sciences Centre

    Halifax, Nova Scotia, B3H 1V7, Canada

  • St. Paul's Hospital

    Vancouver, British Columbia, V6Z 1Y6, Canada

  • The Research Institute of the McGill University

    Montreal, Quebec, H4A 3J1, Canada

  • UC Irvine Medical Center

    Orange, California, 92868, United States

  • Virginia Mason Medical Center

    Seattle, Washington, 97101, United States