Lab-Grown bladder patch could help patients with scarred bladders

NCT ID NCT05054790

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This early study is testing a new approach for people whose bladders have become small and scarred, causing frequent urination and discomfort. Doctors will take a small sample of the patient's own bladder cells, grow them in a lab on a special scaffold to create a 'neo-bladder' patch, and then surgically attach it to the existing bladder to increase its capacity. The study will enroll 10 participants to see if the patch is safe and can improve bladder function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Neo-Bladder construct (lab-grown bladder patch made from the patient's own cells)

What this could lead to

If successful, this could offer a new treatment option for people with a severely scarred, small bladder, potentially improving bladder capacity and reducing frequent urination.

What could go wrong

This is a very early, small study with only 10 participants. The procedure involves major surgery and it is unknown if the lab-grown patch will work safely long-term. It may not lead to a widely available treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CONTRACTED BLADDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atrium Health Wake Forest Baptist

    Winston-Salem, North Carolina, 27157, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact