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New pill nemtabrutinib takes on standard blood cancer drugs in major trial

NCT ID NCT06136559

Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 15, 2026 · Updated 8 times

Summary

This phase 3 trial is testing a new oral drug, nemtabrutinib, against two standard targeted therapies (ibrutinib or acalabrutinib) in 1,200 people with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma. The goal is to see if nemtabrutinib works at least as well in shrinking tumors and better at delaying cancer progression. Participants will be randomly assigned to receive nemtabrutinib or one of the standard drugs chosen by their doctor.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Nemtabrutinib (a targeted oral drug for blood cancer)
What this could lead to
If successful, nemtabrutinib could offer a more effective first-line treatment option for people with chronic lymphocytic leukemia or small lymphocytic lymphoma, potentially delaying disease progression better than current standard therapies.
What could go wrong
This is a large phase 3 trial, but it's still experimental. Nemtabrutinib may not prove superior or even non-inferior to existing drugs, and side effects typical of BTK inhibitors (bleeding, heart rhythm issues, infections) remain a concern.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 1,200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2023

Expected to finish

Sep 2032

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: The main inclusion criteria include but are not limited to the following: * Confirmed diagnosis of CLL/SLL and active disease clearly documented to have a need to initiate therapy. * Has at least 1 marker of disease burden. * Has an Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2 within 7 days before randomization. * Has the ability to swallow and retain oral medication. * Participants who are hepatitis B surface antigen (HBsAg) positive are eligible if they have received hepatitis B virus (HBV) antiviral therapy for at least 4 weeks and have undetectable HBV deoxyribonucleic acid (DNA) viral load before randomization. * Participants with history of hepatitis C virus (HCV) infection are eligible if HCV ribonucleic acid (RNA) viral load is undetectable at screening. * Participants with human immunodeficiency virus (HIV) who meet ALL eligibility criteria. Exclusion Criteria: The main exclusion criteria include but are not limited to the following: * Has an active hepatitis B virus/ hepatitis C virus (HBV/HCV) infection. * Has gastrointestinal (GI) dysfunction that may affect drug absorption. * Has diagnosis of Richter Transformation or active central nervous system (CNS) involvement by CLL/SLL. * Has had acquired immune deficiency syndrome (AIDS)-defining opportunistic infection in the past 12 months before screening. * Has clinically significant cardiovascular disease. * Has hypersensitivity to nemtabrutinib or contraindication to ibrutinib or acalabrutinib, or any of the excipients. * Has history of severe bleeding disorder. * Has known additional malignancy that is progressing or has required active treatment within the past 2 years. * Has received any systemic anticancer therapy for CLL/SLL. * Is currently being treated with p-glycoprotein (P-gp) substrates with a narrow therapeutic index, cytochrome P450 3A (CYP3A) strong or moderate inducers or CYP3A strong inhibitors. * Received prior radiotherapy within 2 weeks of start of study intervention, or radiation-related toxicities, requiring corticosteroids. * Received a live or live-attenuated vaccine within 30 days before the first dose of study intervention. Administration of killed vaccines are allowed. * Has received an investigational agent or has used an investigational device within 4 weeks before study intervention administration. * Has active infection requiring systemic therapy, including intravenous (IV) antibiotics during screening. * Participants who have not adequately recovered from major surgery or have ongoing surgical complications.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic lymphocytic leukemia Small lymphocytic lymphoma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    178 sites in 27 countries. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • AZ Sint-Maarten, Campus Leopoldstraat 2 ( Site 0205)

    RECRUITING

    Mechelen, Antwerpen, 2800, Belgium

  • Aalborg Universitetshospital, Syd ( Site 0403)

    RECRUITING

    Aalborg, North Denmark, 9000, Denmark

  • Akershus Universitetssykehus ( Site 0902)

    RECRUITING

    Lørenskog, Akershus, 1474, Norway

  • Alta Bates Summit Medical Center ( Site 0004)

    ACTIVE_NOT_RECRUITING

    Berkeley, California, 94704, United States

  • Anhui Provincial Cancer Hospital ( Site 2001)

    RECRUITING

    Hefei, Anhui, 230031, China

  • Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1407)

    RECRUITING

    Ankara, 06800, Turkey (Türkiye)

  • Ankara Universitesi Tip Fakultesi Hastanesi-hematology ( Site 1401)

    RECRUITING

    Ankara, 06100, Turkey (Türkiye)

  • Antalya Egitim ve Arastırma Hastanesi ( Site 1409)

    RECRUITING

    Antalya, 7100, Turkey (Türkiye)

  • Aotearoa Clinical Trials ( Site 3201)

    RECRUITING

    Auckland, 2025, New Zealand

  • Arizona Oncology Associates - NAHOA ( Site 8007)

    COMPLETED

    Prescott, Arizona, 86301, United States

  • BC Cancer Kelowna ( Site 0112)

    RECRUITING

    Kelowna, British Columbia, V1Y 5L3, Canada

  • BC Cancer Victoria ( Site 0109)

    RECRUITING

    Victoria, British Columbia, V8R 6V5, Canada

  • Banner MD Anderson Cancer Center ( Site 0059)

    RECRUITING

    Gilbert, Arizona, 85234, United States

  • Banner MD Anderson Cancer Center - University Medical Center Phoenix ( Site 0051)

    RECRUITING

    Phoenix, Arizona, 85006, United States

  • Barnet Hospital ( Site 3005)

    RECRUITING

    Barnet, EN5 3DJ, United Kingdom

  • Bnai Zion Medical Center ( Site 1505)

    RECRUITING

    Haifa, 3339419, Israel

  • Bradfordhill-Clinical Area ( Site 2310)

    RECRUITING

    Santiago, Region M. de Santiago, 8420383, Chile

  • Cancer Care Associates Of York ( Site 0005)

    RECRUITING

    York, Pennsylvania, 17403, United States

  • Cancer Institute Hospital of JFCR ( Site 1906)

    ACTIVE_NOT_RECRUITING

    Koto, Tokyo, 135-8550, Japan

  • Care Access - South Pasadena ( Site 0070)

    RECRUITING

    Pasadena, California, 91105, United States

  • Carolina Oncology Specialists, PA ( Site 0054)

    RECRUITING

    Charlotte, North Carolina, 28207, United States

  • Centre intégré de santé et de services sociaux du Bas Saint-Laurent- Hôpital régional de Rimouski ( Site 0100)

    COMPLETED

    Rimouski, Quebec, G5L 5T1, Canada

  • Centro Medico Monte Carmelo-Oncology ( Site 2706)

    RECRUITING

    Arequipa, Ariqipa, 054, Peru

  • Centro de Infusion Superare ( Site 2602)

    RECRUITING

    Mexico City, Mexico City, 03100, Mexico

  • Champalimaud Foundation ( Site 3102)

    RECRUITING

    Lisbon, Lisbon District, 1400-038, Portugal

  • Chang Gung Medical Foundation-Linkou Branch ( Site 1703)

    RECRUITING

    Taoyuan, 33305, Taiwan

  • Chang Gung Memorial Hospital at Kaohsiung-Division of Hematology and Oncology ( Site 1702)

    RECRUITING

    Kaohsiung City, 833, Taiwan

  • Chiba Cancer Center ( Site 1905)

    ACTIVE_NOT_RECRUITING

    Chiba, 260-8717, Japan

  • Chongqing University Cancer Hospital ( Site 2041)

    RECRUITING

    Chongqing, Chongqing Municipality, 400030, China

  • Chulalongkorn University ( Site 1802)

    RECRUITING

    Pathumwan, Bangkok, 10330, Thailand

  • City Hospital, Nottingham University Hospitals NHS Trust ( Site 3003)

    COMPLETED

    Nottingham, NG5 1PB, United Kingdom

  • Clermont Oncology Center ( Site 0046)

    RECRUITING

    Clermont, Florida, 34711, United States

  • Clínica Alemana de Santiago-Unidad de Investigaciones ( Site 2306)

    RECRUITING

    Santiago, Region M. de Santiago, 7650568, Chile

  • Clínica Anglo Americana ( Site 2701)

    RECRUITING

    Lima, 15073, Peru

  • Constantiaberg Haematology ( Site 1106)

    RECRUITING

    Plumstead, Western Cape, 7800, South Africa

  • Consultants in Medical Oncology and Hematology (CMOH) ( Site 8002)

    RECRUITING

    Broomall, Pennsylvania, 19008, United States

  • Corewell Health-Lemmon Holton Cancer Pavilion ( Site 0011)

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

  • Eastern CT Hematology & Oncology Associates ( Site 0033)

    RECRUITING

    Norwich, Connecticut, 06360, United States

  • Ege Universitesi Hastanesi ( Site 1404)

    RECRUITING

    Izmir, 35100, Turkey (Türkiye)

  • Evangelismos General Hospital of Athens ( Site 0700)

    RECRUITING

    Athens, Attica, 106 76, Greece

  • FALP-UIDO ( Site 2300)

    RECRUITING

    Santiago, Region M. de Santiago, 7500921, Chile

  • Faculty of Medicine Siriraj Hospital-Division of Hematology, Department of Medicine ( Site 1801)

    RECRUITING

    Bangkok, Bangkok, 10700, Thailand

  • Fakultni nemocnice Hradec Kralove-IV. interni hematologicka klinika ( Site 0301)

    RECRUITING

    Hradec Králové, 500 05, Czechia

  • Fakultni nemocnice Olomouc ( Site 0303)

    RECRUITING

    Olomouc, 779 00, Czechia

  • Florida Cancer Specialists - East ( Site 7002)

    RECRUITING

    West Palm Beach, Florida, 33401, United States

  • Florida Cancer Specialists - South ( Site 7001)

    RECRUITING

    Fort Myers, Florida, 33901, United States

  • Fundacion Valle del Lili- CIC-Oncology CIC ( Site 2402)

    RECRUITING

    Cali, Valle del Cauca Department, 760032, Colombia

  • Galilee Medical Center ( Site 1507)

    RECRUITING

    Nahariya, 2201202, Israel

  • General Hospital of Athens "Laiko" ( Site 0704)

    RECRUITING

    Athens, Attica, 115 26, Greece

  • GenesisCare - Bristol ( Site 3011)

    RECRUITING

    Bristol, South Gloucestershire, BS32 4SY, United Kingdom

  • GenesisCare - Cambridge ( Site 3001)

    RECRUITING

    Newmarket, Suffolk, CB8 7XN, United Kingdom

  • GenesisCare - Windsor ( Site 3002)

    RECRUITING

    Windsor, Windsor And Maidenhead, SL4 3HD, United Kingdom

  • Groote Schuur Hospital-Clinical Haematology ( Site 1100)

    RECRUITING

    Cape Town, Western Cape, 7925, South Africa

  • Grupo Médico ASSET SC ( Site 2611)

    RECRUITING

    Benito Juárez, Mexico City, 03100, Mexico

  • Guangxi Medical University Affiliated Tumor Hospital ( Site 2004)

    RECRUITING

    Nanning, Guangxi, 530200, China

  • Gunma University Hospital ( Site 1903)

    ACTIVE_NOT_RECRUITING

    Maebashi, Gunma, 371-8511, Japan

  • HOSPITAL CLÍNIC DE BARCELONA ( Site 1202)

    RECRUITING

    Barcelona, Catalonia, 08036, Spain

  • HOSPITAL UNIVERSITARIO PUERTA DE HIERRO MAJADAHONDA ( Site 1208)

    RECRUITING

    Majadahonda, Madrid, Comunidad de, 28220, Spain

  • HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID ( Site 1209)

    RECRUITING

    Pozuelo de Alarcón, Madrid, 28223, Spain

  • Hadassah Medical Center-Hemato-Oncology ( Site 1500)

    RECRUITING

    Jerusalem, 9112001, Israel

  • Haemalife ( Site 1105)

    RECRUITING

    Kuilsriver, Western Cape, 7580, South Africa

  • Hainan General Hospital ( Site 2018)

    RECRUITING

    Haikou, Hainan, 570311, China

  • Health Pharma Professional Research S.A. de C.V: ( Site 2608)

    COMPLETED

    Mexico City, Mexico City, 03100, Mexico

  • Henan Cancer Hospital-hematology department ( Site 2025)

    RECRUITING

    Zhengzhou, Henan, 450008, China

  • Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital ( Site 1913)

    ACTIVE_NOT_RECRUITING

    Hiroshima, 730-8619, Japan

  • Hokkaido University Hospital ( Site 1900)

    ACTIVE_NOT_RECRUITING

    Sapporo, Hokkaido, 060-8648, Japan

  • Hope - Humanizacao Em Oncologia, Pesquisa E Ensino ( Site 2211)

    RECRUITING

    Ribeirão Preto, São Paulo, 14026-610, Brazil

  • Hospital 9 De Julho ( Site 2206)

    RECRUITING

    São Paulo, São Paulo, 01409-001, Brazil

  • Hospital Erasto Gaertner ( Site 2212)

    RECRUITING

    Curitiba, Paraná, 81520-060, Brazil

  • Hospital Paulistano-Americas Oncologia ( Site 2202)

    RECRUITING

    São Paulo, 01321-001, Brazil

  • Hospital Pulau Pinang ( Site 1602)

    RECRUITING

    George Town, Pulau Pinang, 10450, Malaysia

  • Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 1206)

    RECRUITING

    Barcelona, 08035, Spain

  • Hospital Universitario de Salamanca - Complejo Asistencial U-Servicio de Hematologia ( Site 1201)

    RECRUITING

    Salamanca, 37007, Spain

  • Hunan Cancer Hospital ( Site 2020)

    RECRUITING

    Changsha, Hunan, 410006, China

  • IMAT S.A.S ( Site 2401)

    RECRUITING

    Montería, Departamento de Córdoba, 230002, Colombia

  • InVO Institut für Versorgungsforschung in der Onkologie ( Site 0606)

    RECRUITING

    Koblenz, Rhineland-Palatinate, 56068, Germany

  • Inova Schar Cancer Institute ( Site 0015)

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Institut Català d'Oncologia - L'Hospitalet-Haematology Department ( Site 1207)

    RECRUITING

    L'Hospitalet Del Llobregat, Barcelona, 08908, Spain

  • Institute of hematology&blood disease hospital-Lymphoma ( Site 2005)

    RECRUITING

    Tianjin, Tianjin Municipality, 301617, China

  • Instituto Nacional de Câncer - INCA ( Site 2201)

    RECRUITING

    Rio de Janeiro, 20230-130, Brazil

  • Instituto Português de Oncologia de Lisboa Francisco Gentil ( Site 3103)

    RECRUITING

    Lisbon, Lisbon District, 1099-023, Portugal

  • Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 3100)

    RECRUITING

    Porto, 4200-072, Portugal

  • Intermountain Health St. Mary's Regional Hospital ( Site 0025)

    RECRUITING

    Grand Junction, Colorado, 81501, United States

  • Intermountain Health St. Vincent Regional Hospital - Cancer Centers of Montana ( Site 0052)

    RECRUITING

    Billings, Montana, 59102, United States

  • Japanese Red Cross Osaka Hospital ( Site 1908)

    ACTIVE_NOT_RECRUITING

    Osaka, 543-8555, Japan

  • Jiangsu Province Hospital ( Site 2000)

    RECRUITING

    Nanjing, Jiangsu, 210029, China

  • Jiangxi Provincial Cancer Hospital ( Site 2009)

    RECRUITING

    Nanchang, Jiangxi, 330029, China

  • John Theurer Cancer Center at Hackensack University Medical Center ( Site 0016)

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Karolinska Universitetssjukhuset Solna ( Site 1302)

    RECRUITING

    Stockholm, Stockholm County, 171 64, Sweden

  • Kindai University Hospital ( Site 1909)

    ACTIVE_NOT_RECRUITING

    Sakai, Osaka, 590-0197, Japan

  • Kliniken Maria Hilf ( Site 0603)

    RECRUITING

    Mönchengladbach, North Rhine-Westphalia, 41063, Germany

  • Kobe City Medical Center General Hospital ( Site 1910)

    ACTIVE_NOT_RECRUITING

    Kobe, Hyōgo, 650-0047, Japan

  • Kyushu University Hospital ( Site 1914)

    COMPLETED

    Fukuoka, 812-8582, Japan

  • Liuzhou People's Hospital ( Site 2029)

    RECRUITING

    Liuzhou, Guangxi, 545006, China

  • Lutheran Medical Center ( Site 0027)

    RECRUITING

    Golden, Colorado, 80401, United States

  • Lynn Cancer Center at Boca Raton Regional Hospital ( Site 0063)

    RECRUITING

    Boca Raton, Florida, 33486, United States

  • Maharaj Nakorn Chiang Mai Hospital ( Site 1800)

    RECRUITING

    Muang, Chiang Mai, 50200, Thailand

  • Marmara Universitesi Pendik Egitim Arastirma Hastanesi ( Site 1408)

    ACTIVE_NOT_RECRUITING

    Istanbul, 34899, Turkey (Türkiye)

  • McGill University Health Centre ( Site 0106)

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

  • Medical Oncology Associates, PS (dba Summit Cancer Centers) ( Site 0010)

    RECRUITING

    Spokane, Washington, 99208, United States

  • Mega Medipol ( Site 1412)

    RECRUITING

    Istanbul, 34214, Turkey (Türkiye)

  • MidAmerica Cancer Care, LLC ( Site 0043)

    RECRUITING

    Kansas City, Missouri, 64132, United States

  • Moores Cancer Center ( Site 0003)

    RECRUITING

    La Jolla, California, 92093-0698, United States

  • Nagoya University Hospital ( Site 1907)

    ACTIVE_NOT_RECRUITING

    Nagoya, Aichi-ken, 466-8560, Japan

  • Naresuan University Hospital ( Site 1804)

    RECRUITING

    Muang, Changwat Phitsanulok, 65000, Thailand

  • Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 1000)

    RECRUITING

    Gliwice, Silesian Voivodeship, 44-102, Poland

  • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Kilinka Onkologii I Hematologii ( Site 1004)

    RECRUITING

    Warsaw, Masovian Voivodeship, 02-781, Poland

  • National Cheng Kung University Hospital ( Site 1700)

    RECRUITING

    Tainan, 704302, Taiwan

  • National Taiwan University Hospital ( Site 1701)

    RECRUITING

    Taipei, 10048, Taiwan

  • Netcare Pretoria East Hospital-Alberts Cellular Therapy ( Site 1101)

    RECRUITING

    Pretoria, Gauteng, 0181, South Africa

  • New York Oncology Hematology, P.C. ( Site 0069)

    RECRUITING

    Albany, New York, 12208, United States

  • North Shore Hospital-Department of Haematology ( Site 3200)

    RECRUITING

    Auckland, 0622, New Zealand

  • Odense Universitetshospital-Department of Hematology ( Site 0401)

    RECRUITING

    Odense C, Region Syddanmark, 5000, Denmark

  • Okayama University Hospital ( Site 1912)

    ACTIVE_NOT_RECRUITING

    Okayama, 700-8558, Japan

  • Ondokuz Mays Üniversitesi ( Site 1410)

    RECRUITING

    Samsun, 55280, Turkey (Türkiye)

  • Onkologische Schwerpunktpraxis Kurfuerstendamm ( Site 0600)

    RECRUITING

    Berlin, 10707, Germany

  • Oslo Universitetssykehus Rikshospitalet-Avdeling for blodsykdommer ( Site 0901)

    RECRUITING

    Oslo, 0372, Norway

  • Owensboro Medical Health System ( Site 0066)

    RECRUITING

    Owensboro, Kentucky, 42303, United States

  • Parkview Research Center at Parkview Regional Medical Center ( Site 0002)

    RECRUITING

    Fort Wayne, Indiana, 46845, United States

  • Peking University First Hospital ( Site 2022)

    RECRUITING

    Beijing, Beijing Municipality, 100034, China

  • Peking University Third Hospital-Hematology ( Site 2011)

    RECRUITING

    Beijing, Beijing Municipality, 100191, China

  • Pratia MCM Krakow ( Site 1007)

    RECRUITING

    Krakow, Lesser Poland Voivodeship, 30-727, Poland

  • Pratia Onkologia Katowice ( Site 1009)

    RECRUITING

    Katowice, Silesian Voivodeship, 40-519, Poland

  • Queen Elizabeth Hospital ( Site 1603)

    RECRUITING

    Kota Kinabalu, Sabah, 88586, Malaysia

  • Queen Mary Hospital ( Site 3300)

    RECRUITING

    Hong Kong, Hong Kong

  • RPCI Oncology, PC- Northtowns ( Site 0061)

    RECRUITING

    Williamsville, New York, 14221, United States

  • Rabin Medical Center ( Site 1504)

    RECRUITING

    Petah Tikva, 4941492, Israel

  • Rambam Health Care Campus-Hematology and Bone Marrow Transplantation ( Site 1503)

    RECRUITING

    Haifa, 3109601, Israel

  • Regions Hospital ( Site 0042)

    RECRUITING

    Saint Louis Park, Minnesota, 55416, United States

  • Roskilde Sygehus-Department of Hematology ( Site 0402)

    RECRUITING

    Roskilde, Region Sjælland, 4000, Denmark

  • Roswell Park Cancer Institute ( Site 0023)

    RECRUITING

    Buffalo, New York, 14263, United States

  • Royal Lancaster Infirmary ( Site 3012)

    COMPLETED

    Lancaster, Lancashire, LA1 4RP, United Kingdom

  • Royal North Shore Hospital ( Site 2806)

    COMPLETED

    St Leonards, New South Wales, 2065, Australia

  • SSM Health Dean Medical Group - South Madison Campus Health Research/Circuit Clinical ( Site 0048)

    RECRUITING

    Madison, Wisconsin, 53715, United States

  • Saint Alphonsus Regional Medical Center ( Site 0067)

    RECRUITING

    Boise, Idaho, 83706, United States

  • Saint Elizabeth Healthcare ( Site 0041)

    RECRUITING

    Edgewood, Kentucky, 41017, United States

  • Saint Joseph Hospital ( Site 0026)

    RECRUITING

    Denver, Colorado, 80218, United States

  • Samodzielny Publiczny Zakład Opieki Zdrowotnej MSWiA w Olsztynie-Oddzial Kliniczny Hematologii ( Site 1005)

    RECRUITING

    Olsztyn, Warmian-Masurian Voivodeship, 10-228, Poland

  • Shaanxi provincial people's hospital ( Site 2012)

    RECRUITING

    Xi'an, Shaanxi, 710068, China

  • Shandong Cancer Hospital ( Site 2003)

    RECRUITING

    Jinan, Shandong, 250117, China

  • Shanxi Cancer Hospital ( Site 2033)

    RECRUITING

    Taiyuan, Shanxi, 030000, China

  • Sheba Medical Center-Hemato Oncology ( Site 1501)

    RECRUITING

    Ramat Gan, 5265601, Israel

  • Shimane University Hospital ( Site 1911)

    ACTIVE_NOT_RECRUITING

    Izumo, Shimane, 693-8501, Japan

  • Sisli Florence Nightingale Hastanesi ( Site 1411)

    RECRUITING

    Istanbul, 34381, Turkey (Türkiye)

  • Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 2405)

    RECRUITING

    Valledupar, Cesar Department, 200001, Colombia

  • Songklanagarind hospital ( Site 1803)

    RECRUITING

    Hat Yai, Changwat Songkhla, 90110, Thailand

  • Southeastern Medical Oncology Center ( Site 0049)

    RECRUITING

    Goldsboro, North Carolina, 27534, United States

  • Southern Medical University Nanfang Hospital-Department of Hematopathology ( Site 2006)

    RECRUITING

    Guangzhou, Guangdong, 510515, China

  • Southmead Hospital ( Site 3010)

    COMPLETED

    Bristol, Bristol, City of, BS10 5NB, United Kingdom

  • St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 3006)

    RECRUITING

    London, London, City of, EC1A 7BE, United Kingdom

  • St James's University Hospital ( Site 3004)

    RECRUITING

    Leeds, LS9 7TF, United Kingdom

  • Summit Medical Group Cancer Center ( Site 0007)

    COMPLETED

    Florham Park, New Jersey, 07932, United States

  • Sun Yat-sen University Cancer Center ( Site 2028)

    RECRUITING

    Guangzhou, Guangdong, 510060, China

  • Sykehuset i Vestfold ( Site 0903)

    RECRUITING

    Tønsberg, Vestfold, 3103, Norway

  • Tennessee Oncology, PLLC - Elliston Place Plaza Medical Oncology & Hematology ( Site 0031)

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Tennessee Oncology-Chattanooga ( Site 0045)

    RECRUITING

    Chattanooga, Tennessee, 37404, United States

  • Texas Oncology - Central/South Texas ( Site 8008)

    RECRUITING

    Austin, Texas, 78705, United States

  • Texas Oncology - Northeast Texas ( Site 8012)

    RECRUITING

    Tyler, Texas, 75702, United States

  • Texas Oncology - San Antonio ( Site 8006)

    RECRUITING

    San Antonio, Texas, 78217, United States

  • The Affiliated Hospital of Guizhou Medical University ( Site 2024)

    RECRUITING

    Guiyang, Guizhou, 550004, China

  • The Affiliated Hospital of Xuzhou Medical College ( Site 2013)

    RECRUITING

    Xuzhou, Jiangsu, 221006, China

  • The Center for Cancer and Blood Disorders ( Site 0032)

    RECRUITING

    Fort Worth, Texas, 76104, United States

  • The Churchill Hospital ( Site 3007)

    RECRUITING

    Oxford, Oxfordshire, OX3 7LE, United Kingdom

  • The First Affiliated Hospital of Nanchang University ( Site 2023)

    RECRUITING

    Nanchang, Jiangxi, 330006, China

  • The First Affliated Hospital of Suzhou University ( Site 2027)

    RECRUITING

    Suzhou, Jiangsu, 215000, China

  • The First Hospital of Jilin University-Hematology ( Site 2030)

    RECRUITING

    Changchun, Jilin, 130021, China

  • The Ottawa Hospital - General Campus ( Site 0102)

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

  • The Second Xiangya Hospital of Central South University ( Site 2010)

    RECRUITING

    Changsha, Hunan, 410011, China

  • The first Affiliated Hospital, Zhejiang University School of Medicine-Hematology ( Site 2002)

    RECRUITING

    Hangzhou, Zhejiang, 310003, China

  • Tianjin Medical University Cancer Institute & Hospital-lymphoma ( Site 2019)

    RECRUITING

    Tianjin, Tianjin Municipality, 300060, China

  • Tohoku University Hospital ( Site 1901)

    ACTIVE_NOT_RECRUITING

    Sendai, Miyagi, 980-8574, Japan

  • Tongji Hospital Affiliated to Tongji Medical College of HUST ( Site 2016)

    RECRUITING

    Wuhan, Hubei, 430000, China

  • Trakya University Medical Faculty Hospital-Hematology ( Site 1403)

    RECRUITING

    Edirne, 22030, Turkey (Türkiye)

  • USA Mitchell Cancer Institute ( Site 0014)

    RECRUITING

    Mobile, Alabama, 36604, United States

  • UZ Leuven-Hematology ( Site 0200)

    RECRUITING

    Leuven, Vlaams-Brabant, 3000, Belgium

  • Unidade Local de Saude Gaia/Espinho - Hospital Eduardo Santos Silva ( Site 3107)

    RECRUITING

    Vila Nova de Gaia, Porto District, 4434-502, Portugal

  • Unidade Local de Saude Lisboa Ocidental - Hospital de São Francisco Xavier ( Site 3104)

    RECRUITING

    Lisbon, 1449-005, Portugal

  • Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 3106)

    RECRUITING

    Lisbon, 1649-035, Portugal

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 2015)

    RECRUITING

    Wuhan, Hubei, 430058, China

  • Universitaetsklinikum Ulm. ( Site 0601)

    RECRUITING

    Ulm, Baden-Wurttemberg, 89081, Germany

  • University Hospital and UW Health Clinics ( Site 0006)

    RECRUITING

    Madison, Wisconsin, 53792, United States

  • University Hospital of Alexandroupolis ( Site 0701)

    RECRUITING

    Alexandroupoli, East Macedonia and Thrace, 681 00, Greece

  • University Hospital of Ioannina ( Site 0702)

    RECRUITING

    Ioannina, 455 00, Greece

  • University Malaya Medical Centre ( Site 1604)

    RECRUITING

    Lembah Pantai, Kuala Lumpur, 59100, Malaysia

  • University of Iowa Health Care. ( Site 0017)

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Iowa Health Care. ( Site 0057)

    RECRUITING

    Waukee, Iowa, 50263, United States

  • University of Virginia Cancer Center ( Site 0040)

    RECRUITING

    Charlottesville, Virginia, 22903, United States

  • Universitätsklinikum Halle ( Site 0604)

    RECRUITING

    Halle, Saxony-Anhalt, 06120, Germany

  • Uniwersytecki Szpital Kliniczny nr 1 w Lublinie-Oddział Hematoonkologii-Transplantacji Szpiku i Chem ( Site 1006)

    RECRUITING

    Lublin, Lublin Voivodeship, 20-081, Poland

  • Uniwersyteckie Centrum Kliniczne-Klinika Hematologii i Transplantologii ( Site 1011)

    RECRUITING

    Gdansk, Pomeranian Voivodeship, 80-214, Poland

  • VK&K Studien GbR ( Site 0607)

    RECRUITING

    Landshut, Bavaria, 84036, Germany

  • Virginia Commonwealth University (VCU) Medical Center ( Site 0030)

    RECRUITING

    Richmond, Virginia, 23298, United States

  • Vseobecna fakultni nemocnice v Praze-I. Interní klinika - klinika hematologie ( Site 0302)

    RECRUITING

    Prague, 128 08, Czechia

  • Waikato Hospital-Haematology ( Site 3202)

    RECRUITING

    Hamilton, Waikato Region, 3240, New Zealand

  • West China Hospital, Sichuan University-Head and Neck Oncology ( Site 2026)

    RECRUITING

    Chengdu, Sichuan, 610041, China

  • William Osler Health System ( Site 0103)

    RECRUITING

    Brampton, Ontario, L6R 3J7, Canada

  • Wits Clinical Research ( Site 1102)

    RECRUITING

    Johannesburg, Gauteng, 1864, South Africa

  • Wojewódzki Szpital Specjalistyczny im. J. Korczaka w Słupsku-Oddział Hematologii i Transplantacji ( Site 1013)

    COMPLETED

    Słupsk, Pomeranian Voivodeship, 76-200, Poland

  • Xinjiang Medical University Cancer Hospital - Urumqi ( Site 2014)

    RECRUITING

    Ürümqi, Xinjiang, 830000, China

  • Yamagata University Hospital ( Site 1902)

    ACTIVE_NOT_RECRUITING

    Yamagata, 990-9585, Japan

  • Yitzhak Shamir Medical Center. ( Site 1506)

    RECRUITING

    Ẕerifin, 7033001, Israel

  • Zhejiang Cancer Hospital ( Site 2017)

    RECRUITING

    Hangzhou, Zhejiang, 310022, China

  • hospital universitario de canarias ( Site 1205)

    RECRUITING

    San Cristóbal de La Laguna, Santa Cruz De Tenerife, 38320, Spain

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