Old HIV drug shows promise against rare skin cancer

NCT ID NCT03077451

First seen Jan 11, 2026 · Last updated May 06, 2026 · Updated 14 times

Summary

This study tested whether nelfinavir, a drug originally used for HIV, can shrink Kaposi sarcoma tumors in the skin. It included 36 adults with Kaposi sarcoma, some with HIV and some without. Researchers measured how many people had their tumors shrink or disappear after taking the drug.

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Contacts and locations

Locations

  • African Cancer Institute, Stellenbosch University

    Cape Town, South Africa

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Benaroya Research Institute at Virginia Mason Medical Center

    Seattle, Washington, 98101, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Emory University/Grady Hospital

    Atlanta, Georgia, 30308, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Montefiore Medical Center

    The Bronx, New York, 10461, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    Baltimore, Maryland, 21231-2410, United States

  • Uganda Cancer Institute

    Kampala, Uganda

  • University of Miami

    Miami, Florida, 33136, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.