Breathing vest study halted: new approach for respiratory failure falls short

NCT ID NCT06108284

First seen Feb 20, 2026 · Last updated May 16, 2026 · Updated 13 times

Summary

This study compared a negative pressure ventilation vest (Biphasic Cuirass Ventilation) to standard non-invasive positive pressure ventilation for patients hospitalized with acute hypercapnic respiratory failure. The goal was to see if the vest could resolve breathing failure as effectively as the usual treatment. The study was terminated early and included 50 adults with specific blood gas levels.

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Contacts and locations

Locations

  • University of Missouri Hospitals

    Columbia, Missouri, 65212, United States

Conditions

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