Breathing vest tested for hospital patients – but study stopped early

NCT ID NCT06108284

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a negative pressure vest (Biphasic Cuirass Ventilation) to see if it works as well as standard breathing masks for patients hospitalized with acute hypercapnic respiratory failure (high carbon dioxide levels). The trial planned to enroll 50 adults, but it was terminated early. Because of this, we cannot draw firm conclusions about the device's effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Biphasic cuirass ventilation (a negative pressure vest)

What this could lead to

If it worked, this device could offer an alternative to standard breathing masks for patients with acute breathing failure.

What could go wrong

The trial was terminated early with only 50 participants, so we don't have enough data to know if it works. The device also has specific risks for people with chest injuries or prior surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute respiratory failure respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Missouri Hospitals

    Columbia, Missouri, 65212, United States