New painkiller combo could cut opioid use after major pancreatic surgery

NCT ID NCT07423650

First seen Feb 21, 2026 · Last updated May 01, 2026 · Updated 8 times

Summary

This study tests whether a continuous infusion of nefopam, a non-opioid painkiller, can reduce the need for opioids and improve pain control in 93 adults undergoing pancreatoduodenectomy (a complex pancreatic surgery). Participants will be randomly assigned to receive nefopam, lidocaine, or epidural analgesia alongside standard care. The goal is to find a safer, more effective way to manage post-surgery pain.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Prof. O. Fodor Regional Institute of Gastroenterology and Hepatology

    RECRUITING

    Cluj-Napoca, Cluj, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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