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Neck crack science: ultrasound reveals lasting tissue changes after spinal adjustment

NCT ID NCT07704853

Knowledge-focused Sponsor: Florida Gulf Coast University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 15, 2026 · Last updated Aug 26, 2026 · Updated 5 times

Summary

This study looks at what happens to the small joints in the neck after a chiropractic-style thrust manipulation. Researchers use ultrasound to measure changes in joint capsule length and tissue stiffness right after the adjustment and again 24 hours later. The study involves 40 healthy adults aged 18 to 35 with no neck pain. The goal is to understand whether the adjustment produces lasting physical changes in the joint.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a high-velocity, low-amplitude thrust manipulation applied to the neck (C5-C6)
What this could lead to
If successful, this could help explain how neck adjustments physically affect spinal joints, potentially guiding more targeted treatments for neck pain.
What could go wrong
This is a small, early-stage study in healthy volunteers, not people with neck pain. The measured changes may be too small to matter or may not translate to real-world benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Started

Feb 2025

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy individuals between 18-35 without neck pain * Able to to read and understand English Exclusion Criteria: * autoimmune disease * down syndrome * fusion, fracture * spinal cord compression * vascular pathology * cancer, * any other conditions that induce severe instability * inflammation * weakened bone.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neck pain musculoskeletal

Contacts and locations

Locations

  • Florida Gulf Coast University Marieb Hall 101

    Fort Myers, Florida, 33965, United States

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