UV light zaps mouth sores in transplant patients?
NCT ID NCT00374257
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested whether shining a special UV light inside the mouth could help people with painful mouth sores caused by graft-versus-host disease after a stem cell transplant. Only 11 people took part, and the study was stopped early. The goal was to see if the light treatment was practical and eased symptoms.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Narrow-band UVB phototherapy
- What this could lead to
- If effective, this light treatment could offer a non-drug option to manage painful mouth sores from graft-versus-host disease.
- What could go wrong
- The trial was terminated early and very small (11 people). It is unclear if the light treatment works better than no treatment or has lasting benefits.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
-
Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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