UV light zaps mouth sores in transplant patients?

NCT ID NCT00374257

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether shining a special UV light inside the mouth could help people with painful mouth sores caused by graft-versus-host disease after a stem cell transplant. Only 11 people took part, and the study was stopped early. The goal was to see if the light treatment was practical and eased symptoms.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Narrow-band UVB phototherapy
What this could lead to
If effective, this light treatment could offer a non-drug option to manage painful mouth sores from graft-versus-host disease.
What could go wrong
The trial was terminated early and very small (11 people). It is unclear if the light treatment works better than no treatment or has lasting benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

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