New heart valve offers hope for safer, less invasive treatment

NCT ID NCT05932615

ENROLLING_BY_INVITATION Disease control Sponsor: Abbott Medical Devices Source: ClinicalTrials.gov ↗

Summary

This study is testing a new device called the Navitor valve, which is designed to replace a narrowed aortic heart valve without major open-heart surgery. It will enroll about 1,500 people with severe, symptomatic aortic stenosis who are considered at low or intermediate risk for traditional surgery. The goal is to see if this less invasive procedure is as safe and effective as other available valve replacement methods.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AdventHealth Orlando

Orlando, Florida, 32825, United States
Allegheny General Hospital - ASRI

Pittsburgh, Pennsylvania, 15212, United States
Arkansas Heart Hospital

Little Rock, Arkansas, 72211, United States
Ascension St. Vincent

Indianapolis, Indiana, 46290, United States
Ascension Texas Cardiovascular

Austin, Texas, 78705, United States
Aurora Medical Group

Milwaukee, Wisconsin, 53215, United States
Baptist Hospital of Miami

Miami, Florida, 33176, United States
Baptist Memorial Hospital

Memphis, Tennessee, 38120, United States
Baylor Scott & White - The Heart Hospital Plano

Plano, Texas, 75093, United States
Borgess Medical Center

Kalamazoo, Michigan, 49048, United States
Christ Hospital

Cincinnati, Ohio, 45219, United States
Columbia University Medical Center/NYPH

New York, New York, 10032, United States
East Carolina Heart Institute

Greenville, North Carolina, 27834, United States
Endeavor Health

Evanston, Illinois, 60201, United States
HCA Florida - JFK Hospital

Atlantis, Florida, 33462, United States
HCA Florida Largo Hospital

Largo, Florida, 33770, United States
HCA Florida Ocala Hospital

Ocala, Florida, 34471, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Hillcrest Medical Center

Tulsa, Oklahoma, 74104, United States
Institut de Cardiologie de Montreal (Montreal Heart Inst.)

Montreal, Quebec, H1T 1C8, Canada
Intermountain Health St George Regional Hospital

St. George, Utah, 84790, United States
Kaiser Permanente Fontana Medical Center

Fontana, California, 92335, United States
Lankenau Institute for Medical Research

Wynnewood, Pennsylvania, 19096, United States
Los Robles Regional Medical Center

Thousand Oaks, California, 91360, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Memorial Hermann Hospital

Houston, Texas, 77030, United States
Mission Health & Hospitals

Asheville, North Carolina, 28801, United States
Montefiore Medical Center - Moses Division

New York, New York, 10467, United States
Morristown Medical Center

Morristown, New Jersey, 07962, United States
Mount Sinai Hospital

New York, New York, 10029, United States
MyMichigan Medical Center Midland

Midland, Michigan, 48670, United States
New York University Langone Medical Center - Tisch Hospital

New York, New York, 10010, United States
North Central Heart

Sioux Falls, South Dakota, 57108, United States
Northeast Georgia Medical Center

Gainesville, Georgia, 30501, United States
Northwestern Memorial Hospital

Evanston, Illinois, 60201, United States
Ochsner Medical Center

New Orleans, Louisiana, 70121, United States
Ohio Health Research Institute

Columbus, Ohio, 43113, United States
Piedmont Heart Institute

Atlanta, Georgia, 30309, United States
Pinnacle Health System

Mechanicsburg, Pennsylvania, 17055, United States
Presbyterian Hospital

Albuquerque, New Mexico, 87106, United States
Saint John Regional Hospital - New Brunswick Heart Centre

Saint John, NB E2L 4L4, Canada
Saint Luke's Hospital of Kansas City

Kansas City, Missouri, 64111, United States
Sentara Norfolk General Hospital

Norfolk, Virginia, 23507, United States
Southern California Permanente Medical Group - La Jolla

La Jolla, California, 92037, United States
St. Joseph's Hospital & Medical Center

Phoenix, Arizona, 85013, United States
St. Joseph's Hospital & Medical Center

Denver, Colorado, 80218, United States
St. Michael's Hospital

Toronto, Ontario, M5B 1W8, Canada
St. Paul's Hospital

Vancouver, British Columbia, V6E 1M7, Canada
Stanford University Medical Center

Stanford, California, 94305, United States
Swedish Medical Center

Seattle, Washington, 98122, United States
Tallahassee Research Institute

Tallahassee, Florida, 32308, United States
The Cleveland Clinic

Cleveland, Ohio, 44195, United States
The Methodist Hospital

Houston, Texas, 77030, United States
The Queen's Medical Center

Honolulu, Hawaii, 96814, United States
The Royal Victoria Hospital

Montreal, Quebec, H4A3J1, Canada
University of California at San Francisco

San Francisco, California, 94143, United States
University of Chicago Medical Center

Chicago, Illinois, 60637, United States
University of Michigan

Ann Arbor, Michigan, 48109, United States
University of Ottawa Heart Institute

Ottawa, Ontario, K1Y 4W7, Canada
University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15232, United States
University of Texas Southwestern Medical Center

Dallas, Texas, 75390, United States
University of Virginia Medical Center

Charlottesville, Virginia, 22908, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States
Via Christi Regional Medical Center - St. Francis Campus

Wichita, Kansas, 67226, United States
Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States
Winthrop-University Hospital

Mineola, New York, 11501, United States

Conditions

Explore the condition pages connected to this study.

AORTIC VALVE DISEASE AORTIC VALVE STENOSIS HEART DISEASE STRUCTURAL DISORDER HEART VALVE DISEASES