New hope for tough blood cancers: testing a Triple-Drug attack

NCT ID NCT05564650

Summary

This study is testing a new combination of three drugs—navitoclax, venetoclax, and decitabine—for patients with a high-risk type of blood and bone marrow cancer called myelodysplastic syndrome (MDS) that has come back or hasn't responded to standard treatments. The main goals are to find the safest dose and see if this triple-drug approach can help control the disease. The study involves taking oral pills and receiving intravenous infusions in repeating cycles, with close monitoring for side effects and treatment response.

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Contacts and locations

Locations

  • Sidney Kimmel Cancer Center at Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

Conditions

Explore the condition pages connected to this study.