Researchers launch major study to unravel mysteries of excess male hormones

NCT ID NCT00250159

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This natural history study aims to gather information from up to 3,000 people with genetic conditions that cause too much androgen (male-like hormones), such as congenital adrenal hyperplasia (CAH) and familial male-limited precocious puberty (FMPP). Participants undergo various tests including blood work, glucose tolerance tests, imaging, and cognitive assessments to better understand how excess androgen affects growth, fertility, mood, and overall health. The study does not test any new treatment but will help doctors learn more about these conditions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adrenocortical insufficiency classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency congenital adrenal hyperplasia familial male-limited precocious puberty Familial Testotoxicosis precocious puberty

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medstar Washington Hospital Center

    COMPLETED

    Washington D.C., District of Columbia, 20010, United States

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••