Natural gel could help save failing dental implants
NCT ID NCT07088679
First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This study tests whether a natural bioactive gel, applied after standard deep cleaning, can improve treatment of peri-implantitis — an inflammatory condition that can cause bone loss and implant failure. Twenty adults with at least two affected implants will receive standard cleaning on one implant and cleaning plus the gel on the other. Researchers will compare plaque, bleeding, and bone changes over nine months to see if the gel boosts healing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Sterify Gel (a mucoadhesive hydrogel with hydroxytyrosol, vitamin C derivative, and nisin)
- What this could lead to
- If effective, this gel could become a simple, natural add-on to standard dental cleaning, helping to control peri-implantitis and prevent implant failure.
- What could go wrong
- This is a small, early-stage trial with only 20 participants, so results may not apply broadly. The gel may not provide significant benefit over standard care alone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia
RECRUITINGPavia, Lombardy, 27100, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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