Breathing through your nose may protect your brain while on a ventilator

NCT ID NCT06438302

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether providing gentle nasal airflow to sedated, intubated patients with low oxygen levels can improve brain activity and lung function. Researchers will measure brain waves, blood flow, and lung ventilation under different airflow settings. The goal is to understand if losing nasal breathing during intubation harms the brain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
nasal ventilation via AIRVO 2 device
What this could lead to
If successful, this could show that restoring nasal airflow helps protect brain function in intubated patients.
What could go wrong
This is a very small, early study (22 participants) measuring brain waves and oxygen levels, not clinical outcomes. It may not lead to any change in patient care.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service de Médecine Intensive Réanimation - Hôpital Pitié -Salpêtrière

    RECRUITING

    Paris, 75013, France

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