Shrimp-Derived nanoparticles take on denture fungus

NCT ID NCT07694024

First seen Jul 09, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This study compares a new 1% nanochitosan solution to standard nystatin oral suspension for treating Newton's type II denture stomatitis, a fungal infection causing redness and inflammation under dentures. The trial enrolls 30 complete denture wearers diagnosed by an oral specialist. Researchers measure how well each treatment reduces lesion size, burning sensation, and fungal count, aiming to find a safer, natural alternative.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
1% nanochitosan solution
What this could lead to
If effective, nanochitosan could offer a natural, biocompatible alternative to standard antifungal drugs for treating denture-related mouth inflammation.
What could go wrong
This is a small Phase 2 trial with only 30 participants, so results may not apply broadly. Nanochitosan is still experimental and may not work as well as nystatin.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Dentistry, Kerman University of Medical Sciences

    Kerman, Kerman, 7618868345, Iran

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