Nano drug aims to boost appetite and weight in pancreatic cancer patients

NCT ID NCT07408505

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new nano-formulation of megestrol acetate, a drug used to stimulate appetite and promote weight gain, in patients with advanced pancreatic cancer who suffer from anorexia-cachexia syndrome. The trial will enroll 56 patients and compare those receiving the nano-drug alongside standard chemotherapy to those receiving chemotherapy alone. The goal is to see if the nano-drug helps patients gain more than 5% of their body weight and improves their appetite and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nano-crystalline megestrol acetate

What this could lead to

If it works, this could provide a better-tolerated way to help advanced pancreatic cancer patients gain weight and improve their appetite and quality of life during chemotherapy.

What could go wrong

This is a small, early-phase study with only 56 participants, so results may not apply to all patients. The drug may not significantly improve outcomes, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Body Weight pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Jinan, Shandong 0531

    RECRUITING

    Jinan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••