Nano drug aims to boost appetite and weight in pancreatic cancer patients
NCT ID NCT07408505
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new nano-formulation of megestrol acetate, a drug used to stimulate appetite and promote weight gain, in patients with advanced pancreatic cancer who suffer from anorexia-cachexia syndrome. The trial will enroll 56 patients and compare those receiving the nano-drug alongside standard chemotherapy to those receiving chemotherapy alone. The goal is to see if the nano-drug helps patients gain more than 5% of their body weight and improves their appetite and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- nano-crystalline megestrol acetate
- What this could lead to
- If it works, this could provide a better-tolerated way to help advanced pancreatic cancer patients gain weight and improve their appetite and quality of life during chemotherapy.
- What could go wrong
- This is a small, early-phase study with only 56 participants, so results may not apply to all patients. The drug may not significantly improve outcomes, and side effects are possible.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Jinan, Shandong 0531
RECRUITINGJinan, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New combo therapy targets hard-to-treat pancreatic cancer
- New hope for tough-to-treat pancreatic cancer? drug combo enters phase 2 trial
- Experimental cocktail takes on toughest pancreatic cancer
- New enzyme combo aims to break down pancreatic tumors
- New drug candidate BL-M05D1 enters early human trials for tough cancers