New drug may speed up waking after surgery

NCT ID NCT04713358

First seen Feb 27, 2026 · Last updated May 13, 2026 · Updated 14 times

Summary

This study tested whether nalmefene, a drug that blocks opioids, can improve recovery after general anesthesia. Researchers gave it to 542 adults having elective surgery to see if it shortens time in the recovery room and reduces side effects like slow breathing or grogginess. The goal is to help patients wake up more quickly and safely after surgery.

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Contacts and locations

Locations

  • Renji Hospital

    Shanghai, Shanghai Municipality, 200127, China

  • Shanghai Tong Ren Hospital

    Shanghai, Shanghai Municipality, 200000, China

  • The First Affiliated Hospital of Guangxi Medical University

    Guangxi, Guangxi, 530000, China

  • The First Affiliated Hospital of Zhengzhou University

    Henan, Zhengzhou, 450000, China

Conditions

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