Which drug stops propofol pain best? new trial aims to find out
NCT ID NCT07422558
First seen Feb 23, 2026 · Last updated Jun 23, 2026 · Updated 17 times
Summary
Propofol, a common anesthesia drug, often causes pain when injected. This trial will compare two drugs—nalbuphine and lidocaine—given before propofol to see which reduces that pain better. About 92 adults having elective surgery will take part, and their pain will be measured using a simple scale.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nalbuphine and lidocaine
What this could lead to
If one drug works better, it could become a standard way to prevent pain from propofol injections.
What could go wrong
This is a small, early-stage trial with only 92 people. Previous studies have had conflicting results, so neither drug may prove clearly better.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.