Nasal spray vs needle: new study tests easier way to mature eggs for freezing
NCT ID NCT06763926
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a nasal spray (nafarelin) to a standard injection (triptorelin) for triggering final egg maturation in women freezing their eggs for fertility preservation. About 154 women will be randomly assigned to one of the two triggers during ovarian stimulation. The main goal is to see if the nasal spray works as well as the injection at producing mature eggs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nafarelin (intranasal spray) and triptorelin (injection)
What this could lead to
If nafarelin works as well as triptorelin, it could offer a needle-free option for triggering final egg maturation, making fertility preservation more comfortable.
What could go wrong
This is a small, early-phase non-inferiority trial (154 participants) comparing two established drugs; it may not show nafarelin is as effective, and individual responses vary.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Departamento de Ginecología Obstetricia y Reproducción. Hospital Universitari Dexeus
Barcelona, 08037, Spain
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Dexeus Mujer Reus
Reus, Tarragona, 43202, Spain
Contact
Contact
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Dexeus Mujer Sabadell
Sabadell, Barcelona, 08203, Spain
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Contact
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Dexeus Mujer Sant Cugat
Sant Cugat del Vallès, Barcelona, 08190, Spain
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Contact
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Dexeus Mujer Tarragona
Tarragona, 43206, Spain
Contact
Contact