Scientists test common supplement to boost Cancer-Killing cell therapy

NCT ID NCT05081479

Summary

This study is testing whether adding an over-the-counter antioxidant called N-Acetylcysteine (NAC) to a powerful cell therapy (CAR-T) is safe for people with lymphoma. Researchers want to find the highest dose of NAC that causes few or mild side effects when given alongside the CAR-T therapy. The goal is to see if NAC can help the CAR-T cells work better by improving the environment around the tumor.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.