Could a common supplement help prevent schizophrenia?

NCT ID NCT05142735

First seen Mar 31, 2026 · Last updated May 13, 2026 · Updated 7 times

Summary

This study tests whether N-acetylcysteine (NAC), a safe antioxidant supplement, can reduce early psychosis-like symptoms in 90 people at high risk for schizophrenia. Participants take NAC or a placebo for 8 weeks, and researchers measure changes in symptoms and brain activity. The goal is to find a well-tolerated treatment option for those with early warning signs of schizophrenia.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre for Addiction and Mental Health

    RECRUITING

    Toronto, Ontario, M5T 1R8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.