Could a common supplement tame lupus? new trial investigates

NCT ID NCT00775476

First seen May 01, 2026 ยท Last updated May 01, 2026

Summary

This study tests whether N-acetylcysteine (NAC), a supplement, can help control lupus, a chronic disease where the immune system attacks the body. About 290 adults with lupus will first take NAC for 3 months to find a safe dose, then half will continue NAC and half will get a placebo for another 10 months. The goal is to see if NAC reduces lupus symptoms and improves immune function without serious side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Contacts and locations

Locations

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30307, United States

  • Hospital for Special Surgery

    New York, New York, 10021, United States

  • Penn State MS Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • SUNY Upstate Medical University

    Syracuse, New York, 13210, United States

  • St. Luke's University Health Network

    Allentown, Pennsylvania, 18102, United States

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • University of Columbia

    New York, New York, 10032, United States

  • University of Kentucky

    Lexington, Kentucky, 40536, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15261, United States

  • VA Medical Center

    Oklahoma City, Oklahoma, 73104, United States

  • Yale Center for Clinical Investigation

    New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.