Can a common supplement calm emotional storms in kids?

NCT ID NCT07323446

First seen Jan 08, 2026 · Last updated May 14, 2026 · Updated 21 times

Summary

This study tests whether N-Acetylcysteine (NAC), a supplement, can help children ages 6-12 with emotional dysregulation (intense mood swings, anger, or irritability). About 80 kids with the condition will receive NAC or a placebo for 8 weeks, while 40 typically developing kids serve as a comparison group. Brain scans (MRI) will be used to see how the treatment affects the brain. The goal is to see if NAC can ease symptoms like mania and depression.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts Institute of Technology

    Cambridge, Massachusetts, 02139, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.