New tool predicts chemo sickness; drug shows promise

NCT ID NCT04817189

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested if the drug Akynzeo can prevent nausea and vomiting in cancer patients getting moderate chemotherapy who are at high risk based on a special prediction tool. Over 400 adults took part. The goal was to see if Akynzeo works better than standard care over three rounds of chemo.

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Conditions

The condition(s) this trial relates to.

cancer chemotherapy-induced toxicity Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Complejo Hospitalario Universitario de A Coruña

    A Coruña, 15006, Spain

  • Evang. Kliniken Essen-Mitte

    Essen, Germany

  • Frauenklinik St. Louise

    Paderborn, Germany

  • General University Hospital in Prague

    Prague, Czechia

  • General University Hospital of Heraklion

    Heraklion, Greece

  • Hospital General Universitario Gregorio Marañón

    Madrid, 28007, Spain

  • Hospital Universitario de Salamanca

    Salamanca, 37007, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, 0802, Spain

  • Klinikum Ernst von Bergmann gemeinnützige GmbH

    Potsdam, Germany

  • München Klinik Neuperlach

    München, Germany

  • Shanghai Chest Hospital

    Shanghai, China

  • Shanghai Ninth People´s Hospital

    Shanghai, China

  • Shanghai Obstetrics and Gynecology Hospital

    Shanghai, China

  • Sotiria General Hospital, 3rd Deúpartment of Medicine, School of Medicine, National and Kapodistrian University of Athens

    Athens, Greece

  • Swiss Medical Network - Clinique de Genolier

    Genolier, Switzerland

  • The Royal Marsden Hospital

    London, United Kingdom

  • Thomayerova nemocnice

    Prague, 14059, Czechia

  • University Hospital Basel

    Basel, Switzerland

  • Universitätsmedizin Mannheim

    Mannheim, Germany