Can special contacts or atropine drops slow nearsightedness in kids?

NCT ID NCT05815784

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This trial tests three approaches to slow the progression of nearsightedness (myopia) in children aged 5 to 12: daily atropine eye drops, MiSight contact lenses, and NaturalVue multifocal contact lenses. Over two years, researchers will measure changes in eye length and prescription strength to see which method works best. The study also looks at how well younger children tolerate contact lenses and how consistently each treatment is used.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
atropine 0.05% eye drops, MiSight contact lenses, or NaturalVue multifocal contact lenses
What this could lead to
If successful, this could identify the most effective and practical myopia-control option for children, potentially slowing vision deterioration and reducing future eye-health risks.
What could go wrong
This is a phase 2 trial, so results are preliminary. Side effects like light sensitivity or contact-lens intolerance may limit real-world use, and individual responses can vary.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    Chicago, Illinois, 60611, United States

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Other studies related to the condition(s) this trial covers.