CAR-T therapy tested as First-Line treatment for myeloma

NCT ID NCT06045806

Ongoing Disease control Sponsor: Celgene Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a personalized immune cell therapy (called ide-cel) to standard maintenance medication (lenalidomide) works better than the standard medication alone for adults with newly diagnosed multiple myeloma. It focuses on patients who had a stem cell transplant but whose cancer did not respond as well as hoped. The main goal is to see if the combination keeps the cancer from getting worse for a longer time.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AdventHealth Orlando

Orlando, Florida, 32804, United States
Asan Medical Center

Seoul, Seoul-teukbyeolsi, 05505, South Korea
Ascension Providence Hospital

Southfield, Michigan, 48075, United States
Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu

Nantes, Pays de la Loire Region, 44000, France
Chiba University Hospital

Chiba, 260-8677, Japan
Chonnam National University Hwasun Hospital

Hwasun, Jeonranamdo, 58128, South Korea
Colorado Blood Cancer Institute

Denver, Colorado, 80218, United States
Columbia University Irving Medical Center

New York, New York, 10032, United States
Henri Mondor Hospital

Créteil, Val-de-Marne, 94010, France
Hokkaido University Hospital

Sapporo, Hokkaido, 060-8648, Japan
Hopital Claude Huriez - CHU de Lille

Lille, Nord, 59000, France
Hospital Clínic de Barcelona

Barcelona, Catalunya [Cataluña], 08036, Spain
Hospital Universitari i Politecnic La Fe

Valencia, 46026, Spain
Hyogo Medical University Hospital

Nishinomiya, Hyōgo, 663-8501, Japan
Institut Paoli-Calmettes

Marseille, Bouches-du-Rhône, 13273, France
Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE

Toulouse, 31100, France
Japanese Red Cross Medical Center

Shibuya-ku, Tokyo, 150-8935, Japan
Kanazawa University Hospital

Kanazawa, Ishikawa-ken, 920-8641, Japan
Kyushu University Hospital

Fukuoka, 812-8582, Japan
Local Institution - 0001

Hamilton, Ontario, L8V5C2, Canada
Local Institution - 0004

Melbourne, Victoria, 3000, Australia
Local Institution - 0005

Brisbane, Queensland, 4029, Australia
Local Institution - 0006

Melbourne, Victoria, 3004, Australia
Local Institution - 0007

Camperdown, New South Wales, 2050, Australia
Local Institution - 0008

Melbourne, Victoria, 3065, Australia
Local Institution - 0011

Murdoch, Western Australia, 6150, Australia
Local Institution - 0012

Pamplona, Navarre, 31008, Spain
Local Institution - 0013

Salamanca, 37007, Spain
Local Institution - 0017

L'Hospitalet Del Llobregat, Barcelona [Barcelona], 08908, Spain
Local Institution - 0020

Badalona, Barcelona [Barcelona], 08916, Spain
Local Institution - 0021

Madrid, 28041, Spain
Local Institution - 0022

Gliwice, Silesian Voivodeship, 44-101, Poland
Local Institution - 0023

Warsaw, Masovian Voivodeship, 02-776, Poland
Local Institution - 0024

Poznan, 60-569, Poland
Local Institution - 0026

Gdansk, 80-952, Poland
Local Institution - 0027

Lublin, Lublin Voivodeship, 20-090, Poland
Local Institution - 0028

Villejuif, Val-de-Marne, 94805, France
Local Institution - 0029

Poitiers, Vienne, 86021, France
Local Institution - 0031

Paris, Île-de-France Region, 75571, France
Local Institution - 0038

Seoul, Seoul Teugbyeolsi, 06351, South Korea
Local Institution - 0043

Seoul, Seoul Teugbyeolsi, 06591, South Korea
Local Institution - 0046

Pierre-Bénite, Rhône, 69310, France
Local Institution - 0047

Pessac, Aquitaine, 33600, France
Local Institution - 0055

Beersheba, Southern District, 8410101, Israel
Local Institution - 0056

Haifa, 31096, Israel
Local Institution - 0057

Ramat Gan, Central District, 5262100, Israel
Local Institution - 0058

Petah Tikva, Central District, 4910021, Israel
Local Institution - 0059

Jerusalem, 9112001, Israel
Local Institution - 0060

Thessaloniki, Thessaloníki, 570 10, Greece
Local Institution - 0061

Athens, Attikí, 106 76, Greece
Local Institution - 0062

Chaïdári, Attikí, 12462, Greece
Local Institution - 0063

Pátrai, Achaḯa, 26504, Greece
Local Institution - 0064

Rozzano, Milano, 20089, Italy
Local Institution - 0065

Bologna, 40138, Italy
Local Institution - 0066

Roma, 00161, Italy
Local Institution - 0069

Oslo, 0372, Norway
Local Institution - 0070

Odense, Region Syddanmark, 5000, Denmark
Local Institution - 0071

Shimotsuke, 329-0498, Japan
Local Institution - 0072

Heidelberg, Baden-Wurttemberg, 69120, Germany
Local Institution - 0073

Cologne, North Rhine-Westphalia, 50937, Germany
Local Institution - 0074

Würzburg, 97080, Germany
Local Institution - 0076

Hamburg, 20246, Germany
Local Institution - 0077

Nuremberg, Bavaria, 90419, Germany
Local Institution - 0078

Ulm, Baden-Wurttemberg, 89081, Germany
Local Institution - 0079

Dresden, 01307, Germany
Local Institution - 0080

London, London, City of, SE5 9RS, United Kingdom
Local Institution - 0082

Paris, 75010, France
Local Institution - 0083

Anderlecht, Bruxelles-Capitale, Région de, 1070, Belgium
Local Institution - 0084

Brussels, Bruxelles-Capitale, Région de, 1090, Belgium
Local Institution - 0085

Isehara, Kanagawa, 259-1193, Japan
Local Institution - 0087

Leipzig, Saxony, 04103, Germany
Local Institution - 0088

Tel Aviv, Tell Abīb, 6423906, Israel
Local Institution - 0089

Salzburg, 5020, Austria
Local Institution - 0090

Vienna, 1090, Austria
Local Institution - 0091

Bucharest, 022328, Romania
Local Institution - 0093

Birmingham, England, B15 2TH, United Kingdom
Local Institution - 0094

London, London, City of, W12 0HS, United Kingdom
Local Institution - 0095

Warsaw, Masovian Voivodeship, 02-097, Poland
Local Institution - 0104

Atlanta, Georgia, 30342, United States
Local Institution - 0109

Houston, Texas, 77030, United States
Local Institution - 0113

Sacramento, California, 95817, United States
Local Institution - 0115

Essen, 45122, Germany
Local Institution - 0121

Atlanta, Georgia, 30322, United States
Local Institution - 0124

Austin, Texas, 78704, United States
Local Institution - 0126

Orange, California, 92868, United States
Local Institution - 0131

Los Angeles, California, 90095, United States
Local Institution - 0132

Philadelphia, Pennsylvania, 19104, United States
Local Institution - 0133

Edmonton, Alberta, T6G 1Z2, Canada
Local Institution - 0134

Montreal, Quebec, H1T 2M4, Canada
Local Institution - 0144

Brussels, Bruxelles-Capitale, Région de, 1200, Belgium
Local Institution - 0151

Boston, Massachusetts, 02215, United States
M Health Fairview Clinics and Surgery Center

Minneapolis, Minnesota, 55455, United States
Nagoya City University Hospital

Nagoya, Aichi-ken, 467-8602, Japan
Novant Health Cancer Institute - Elizabeth

Charlotte, North Carolina, 28204, United States
Okayama University Hospital

Okayama, 700-8558, Japan
Seoul National University Hospital

Seoul, Seoul Teugbyeolsi, 03080, South Korea
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
University of Texas MD Anderson Cancer Center

Houston, Texas, 77030, United States
Washington University School of Medicine

St Louis, Missouri, 63108, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Yale University School of Medicine

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

MULTIPLE MYELOMA