New hope for myelofibrosis patients who stopped responding to standard treatment

NCT ID NCT06887803

Summary

This early-stage study is testing whether adding a new drug called roginolisib to the standard treatment ruxolitinib is safe and tolerable for adults with myelofibrosis, a serious bone marrow cancer. It aims to help patients whose disease has not responded well to ruxolitinib alone, looking to reduce symptoms like spleen enlargement and fatigue. The study will enroll about 26 participants to first check safety and then gather more information on potential benefits.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Avigunda Gran via de l'Hospitalet 199-203, 08908 L'Hospitalet de Llobregat

    RECRUITING

    Barcelona, 08908, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Azienda Ospedaliero Universitaria Careggi Firenze, Struttura Complessa di Ematologia

    RECRUITING

    Florence, Florence, 50134, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Azienda Sanitario Universitaria Friuli Centrale

    RECRUITING

    Udine, 33100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Universitario de Salamanca

    RECRUITING

    Salamanca, 37007, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • IRCCS Clinical Institute Humanitas

    RECRUITING

    Rozzano, Milan, 20089, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Istituto di Ematolgia e Oncologia Medica

    RECRUITING

    Bologna, 40138, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Vall d'Hebron University Hospital

    RECRUITING

    Barcelona, 08035, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.