Can a phone app curb HIV and drug use in homeless teens?

NCT ID NCT06074354

Recruiting now Prevention Sponsor: The University of Texas Health Science Center, Houston Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a smartphone app called MY-RIDE that offers just-in-time support and nurse-led sessions to help homeless youth reduce substance use and adopt HIV prevention methods like PrEP. 450 participants aged 15-24 who are homeless, use substances, and are sexually active will be followed for 15 months. The goal is to see if the app leads to less drug use and more HIV prevention behaviors compared to standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: MY-RIDE smartphone app with nurse-led sessions and just-in-time support
What this could lead to: If it works, this could provide an effective way to help homeless youth reduce substance use and adopt HIV prevention strategies like PrEP.
What could go wrong: This is an early-stage behavioral trial with no drug involved, so results may be modest. The app relies on self-report and phone access, which may limit real-world impact.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV INFECTIONS

Contacts and locations

Locations

The University of Texas Health Science Center at Houston
RECRUITING

Houston, Texas, 77030, United States

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