Mpox vaccine gets a production upgrade: new cell recipe under trial
NCT ID NCT07199569
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the MVA-BN mpox vaccine (Jynneos) works as well when made in quail cells instead of chicken cells. About 970 healthy adults aged 18 to 49 will receive two doses four weeks apart. Researchers will compare immune responses and side effects between the two versions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- MVA-BN vaccine (Jynneos)
- What this could lead to
- If successful, this could confirm that the vaccine works just as well when made in quail cells, making production more flexible and reliable.
- What could go wrong
- This is a mid-stage trial comparing manufacturing methods, not testing a new vaccine. It may not show a clear difference, and results may not apply to older adults or those with health issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Accellacare - Knoxville
Knoxville, Tennessee, 37938, United States
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Accellacare Research of Salisbury
Salisbury, North Carolina, 28144, United States
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Accellacare and McFarland Clinic
Ames, Iowa, 50010, United States
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Accellacare of Cary - Cary Medical Group
Cary, North Carolina, 27518, United States
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Accellacare of Charleston
Mt. Pleasant, South Carolina, 29464, United States
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Avacare
Austin, Texas, 78705, United States
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Avacare
Fort Worth, Texas, 76135, United States
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Johnson County ClinTrials, LLC
Lenexa, Kansas, 66219, United States
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Rochester Clinical Research, Inc
Rochester, New York, 14609, United States
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Velocity Clinical Research
Suffolk, Virginia, 23435, United States
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