Experimental cell therapy targets rare Muscle-Weakening disease

NCT ID NCT05451212

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested a new cell therapy called MuSK-CAART in 7 people with a rare, severe form of myasthenia gravis (MuSK MG). The treatment uses a patient's own immune cells, modified to attack the harmful antibodies causing the disease. The main goal was to check safety and find the right dose, with the hope of achieving long-term remission.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Oregon Health & Science University (OHSU)

    Portland, Oregon, 97239, United States

  • UC Davis, Department of Neurology

    Sacramento, California, 95817, United States

  • UC Irvine, Department of Neurology

    Orange, California, 92868, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.