Lullabies as medicine: can music ease opioid withdrawal in newborns?

NCT ID NCT03533985

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This study tests whether music therapy can help newborns who are withdrawing from opioids they were exposed to before birth. Researchers will try six different music-based approaches, including parent-sung lullabies and rhythmic sounds, to see if they calm the babies and improve vital signs, sleep, and feeding. The goal is to find a gentle, non-drug way to ease withdrawal symptoms in the neonatal intensive care unit.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
music therapy interventions including Song of Kin (parent-led lullabies) and rhythmic entrainment (Gato box)
What this could lead to
If effective, music therapy could offer a drug-free way to soothe withdrawal symptoms in newborns and reduce the need for medication.
What could go wrong
This is a small pilot study, so results may not be definitive. Music therapy may not significantly improve outcomes, and individual responses can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NAS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Drexel University/Hahnemann Hospital-College of Nursing and Health Professions

    RECRUITING

    Philadelphia, Pennsylvania, 19102, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Joseph M. Sanzari Children's Hospital

    RECRUITING

    Hackensack, New Jersey, 07601, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Maria Fareri Children's Hospital

    RECRUITING

    Valhalla, New York, 10595, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-••••

    Contact

  • Mount Sinai West

    RECRUITING

    New York, New York, 10003, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Northwell Health

    RECRUITING

    New Hyde Park, New York, 11040, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Tulane University Hospital

    RECRUITING

    New Orleans, Louisiana, 70112, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

More trials for these conditions

Other studies related to the condition(s) this trial covers.