Music and brain zaps show promise for rare movement disorder
NCT ID NCT05073471
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether combining music-based movement cues (patterned sensory enhancement) with mild brain stimulation can improve arm and hand function in people with corticobasal syndrome, a rare brain disorder. Twenty participants will be split into two groups: one receiving music therapy alone, the other receiving music therapy plus brain stimulation. The goal is to see if these safe, non-invasive approaches can help with daily tasks and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Patterned Sensory Enhancement (music therapy) and transcranial direct current stimulation (mild brain stimulation)
- What this could lead to
- If it works, this could point toward a non-invasive, drug-free way to improve arm and hand function and quality of life for people with corticobasal syndrome.
- What could go wrong
- This is a very small, early-stage study with only 20 participants, so results may not apply to everyone. The improvements may be modest or not last long-term.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Johns Hopkins School of Medicine
Baltimore, Maryland, 21205, United States
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