How does losing more of a leg change strength and balance? researchers measure the difference
NCT ID NCT07032233
First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time
Summary
Researchers are studying how muscle strength, balance, and walking ability differ in people with an above-knee amputation. The study measures strength at the hip, knee, and ankle of the intact leg, tests balance on a force platform, and records how far participants walk in six minutes. By comparing the length of the leftover limb with the intact leg, the team wants to see whether losing more of the leg relates to weaker muscles or worse balance. The goal is to inform rehabilitation programs that help people with amputations move better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If researchers find links between residual limb length, muscle strength, and balance, this could help shape rehabilitation programs that target the right muscles and improve walking for people with above-knee amputations.
- What could go wrong
- This is a small observational study of 15 people, so it cannot prove cause and effect. The findings may not apply to people outside the narrow age and health range studied, and they may not translate into better rehabilitation on their own.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 15 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants will be selected from the population of adults with unilateral transfemoral amputation who are able to ambulate independently with a prosthesis. The target population includes individuals between the ages of 18 and 50 who have been using a prosthesis for at least 6 months. Eligible participants must be literate and free from cardiovascular, orthopedic, cognitive, or neurological conditions that could interfere with gait, balance, or muscle strength. Recruitment may occur through rehabilitation clinics, prosthetics centers, or community referrals.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Individuals will be included in the study if they: Are between 18 and 50 years of age Are literate Have unilateral transfemoral amputation Have no cardiovascular, orthopedic, cognitive, or neurological conditions that could negatively affect balance, gait, or muscle strength Are able to ambulate independently with a prosthesis Have been walking for at least 6 months Voluntarily agree to participate in the study Exclusion Criteria: Participants will be excluded from the study if: They develop complications such as pain (rated 3 or higher on the Visual Analog Scale) or stump irritation during the course of the study Their residual limb length is less than 25 cm from the greater trochanter, which exceeds the limitations of the isokinetic dynamometer attachments used in the study They voluntarily withdraw from the study - in such cases, their data will be removed from the records
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Gaziler Physical Therapy and Rehabilitation Training and Research Hospital
RECRUITINGAnkara, Ankara, 06800, Turkey (Türkiye)
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