How does losing more of a leg change strength and balance? researchers measure the difference

NCT ID NCT07032233

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Recruiting now This study
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By invitation only
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First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers are studying how muscle strength, balance, and walking ability differ in people with an above-knee amputation. The study measures strength at the hip, knee, and ankle of the intact leg, tests balance on a force platform, and records how far participants walk in six minutes. By comparing the length of the leftover limb with the intact leg, the team wants to see whether losing more of the leg relates to weaker muscles or worse balance. The goal is to inform rehabilitation programs that help people with amputations move better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers find links between residual limb length, muscle strength, and balance, this could help shape rehabilitation programs that target the right muscles and improve walking for people with above-knee amputations.
What could go wrong
This is a small observational study of 15 people, so it cannot prove cause and effect. The findings may not apply to people outside the narrow age and health range studied, and they may not translate into better rehabilitation on their own.

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Study facts

What this study's own registry entry says, in plain language.

Participants

About 15 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will be selected from the population of adults with unilateral transfemoral amputation who are able to ambulate independently with a prosthesis. The target population includes individuals between the ages of 18 and 50 who have been using a prosthesis for at least 6 months. Eligible participants must be literate and free from cardiovascular, orthopedic, cognitive, or neurological conditions that could interfere with gait, balance, or muscle strength. Recruitment may occur through rehabilitation clinics, prosthetics centers, or community referrals.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Individuals will be included in the study if they: Are between 18 and 50 years of age Are literate Have unilateral transfemoral amputation Have no cardiovascular, orthopedic, cognitive, or neurological conditions that could negatively affect balance, gait, or muscle strength Are able to ambulate independently with a prosthesis Have been walking for at least 6 months Voluntarily agree to participate in the study Exclusion Criteria: Participants will be excluded from the study if: They develop complications such as pain (rated 3 or higher on the Visual Analog Scale) or stump irritation during the course of the study Their residual limb length is less than 25 cm from the greater trochanter, which exceeds the limitations of the isokinetic dynamometer attachments used in the study They voluntarily withdraw from the study - in such cases, their data will be removed from the records

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As listed by the trial registrant

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How to take part

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Contacts and locations

Locations

  • Gaziler Physical Therapy and Rehabilitation Training and Research Hospital

    RECRUITING

    Ankara, Ankara, 06800, Turkey (Türkiye)

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