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Why arm trouble lingers after breast cancer: muscle oxygen under the microscope

NCT ID NCT07818811

Knowledge-focused Sponsor: Pamukkale University Source: ClinicalTrials.gov ↗

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Cancelled before anyone took part.

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When the status isn't known

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First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time

Summary

Many breast cancer survivors struggle with arm and shoulder problems long after treatment ends. Researchers at Pamukkale University are measuring muscle oxygen levels in the upper arm using a light-based sensor, along with arm strength and daily function, in 80 women who finished treatment for early-stage breast cancer and in healthy volunteers. By comparing the two groups, they aim to understand whether poor oxygen delivery to muscles helps explain these lasting difficulties and how rehabilitation could target it.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers find a link between poor muscle oxygen and arm problems, this could shape exercise programs that help breast cancer survivors regain strength and daily independence.
What could go wrong
This is a small observational study, so it can show associations but not prove cause and effect. Results may not apply to all survivors, and no treatment is tested here.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

breast cancer survivors: At least 40 cases of patients aged 18 and older who met the inclusion criteria, who had undergone breast surgery (at least 6 months to a maximum of 15 years had elapsed since mastectomy and curative treatment), and who were being followed up at the General Surgery Breast Clinic of Pamukkale University healty individuals: At least 40 healthy individuals who are undergoing routine follow-up at the General Surgery Breast Clinic of Pamukkale University, have no history of cancer, and meet the criteria for inclusion in the control group

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals diagnosed with stage 1, 2, or 3 unilateral breast cancer * who completed breast cancer treatment at least 6 months ago * whose clinical condition is stable Exclusion Criteria: * having an upper extremity disability or musculoskeletal disorder that could affect physical performance * having undergone bilateral breast surgery * development of recurrence or metastasis * uncontrolled chronic cardiopulmonary diseases (hypertension, heart failure, peripheral artery disease, COPD, asthma, etc.), uncontrolled chronic conditions such as diabetes or neuromotor disorders, anemia, smoking, or cognitive impairment * having participated in a regular exercise program within the last 6 months

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Conditions

The condition(s) this trial relates to.

breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer survivors

How to take part

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