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New drug combo tested for Tough-to-Treat blood cancer relapse

NCT ID NCT04191616

Completed Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

Summary

This study tested a combination of three drugs—carfilzomib, pomalidomide, and dexamethasone—for adults with multiple myeloma whose cancer had returned once or twice after previous treatments. The main goal was to see how well this combination worked to control the disease and how long the response lasted. It involved 54 participants whose cancer had stopped responding to a common prior drug called lenalidomide.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aalborg Universitetshospital

    Aalborg, 9000, Denmark

  • Aarhus Universitetshospital

    Aarhus N, 8200, Denmark

  • Affiliated Oncologists, LLC

    Chicago Ridge, Illinois, 60415, United States

  • Alexandra Hospital

    Athens, 11528, Greece

  • Asklepios Klinik Altona

    Hamburg, 22763, Germany

  • Azienda Ospedaliera Citta della Salute e della Scienza di Torino Ospedale Molinette

    Torino, 10126, Italy

  • Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona

    Ancona, 60126, Italy

  • Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

    Brescia, 25123, Italy

  • Azienda Unita Sanitaria Locale LE Presidio Ospedaliero Vito Fazzi Polo Oncologico Giovanni Paolo II

    Lecce, 73100, Italy

  • Baylor Charles A Sammons Cancer Center at Dallas

    Dallas, Texas, 75246, United States

  • Blue Ridge Cancer Care

    Roanoke, Virginia, 24014, United States

  • CHU Grenoble Alpes

    Grenoble, 38043, France

  • Centre Hospitalier Régional Universitaire de Lille - Hôpital Claude Huriez

    Lille, 59037, France

  • Centre Hospitalier Universitaire de Bordeaux - Hôpital Haut Lévêque

    Pessac, 33604, France

  • Centre Hospitalier Universitaire de Nantes

    Nantes, 44093, France

  • Centre Hospitalier de Saint Quentin

    Saint-Quentin, 02321, France

  • Clinique Sainte Anne

    Strasbourg, 67000, France

  • General Hospital Evangelismos

    Athens, 10676, Greece

  • General Hospital of Thessaloniki Georgios Papanikolaou

    Thessaloniki, 57010, Greece

  • General University Hospital of Patras Panagia i Voithia

    Pátrai, 26504, Greece

  • Hospital Clinic i Provincial de Barcelona

    Barcelona, Catalonia, 08036, Spain

  • Hospital Clinico Universitario de Salamanca

    Salamanca, Castille and León, 37007, Spain

  • Hospital Universitari Germans Trias i Pujol

    Badalona, Catalonia, 08916, Spain

  • Hospital Universitari i Politecnic La Fe

    Valencia, Valencia, 46026, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Institut Universitaire du Cancer Toulouse Oncopole

    Toulouse, 31059, France

  • Klinikum Chemnitz gGmbH

    Chemnitz, 09113, Germany

  • Minnesota Oncology Hematology PA

    Saint Paul, Minnesota, 55102, United States

  • North Estonia Medical Centre

    Tallinn, 13419, Estonia

  • Oncology Hematology Care Incorporated

    Cincinnati, Ohio, 45236, United States

  • Policlinico Universitario Agostino Gemelli

    Roma, 00168, Italy

  • Rocky Mountain Cancer Centers Denver Midtown

    Denver, Colorado, 80218, United States

  • Sjaellands Universitetshospital

    Roskilde, 4000, Denmark

  • Texas Oncology - Austin Midtown

    Austin, Texas, 78705, United States

  • Texas Oncology, Fort Worth

    Fort Worth, Texas, 76104, United States

  • Texas Oncology- Tyler

    Tyler, Texas, 75702, United States

  • Theagenion Cancer Hospital of Thessaloniki

    Thessaloniki, 54007, Greece

  • US Oncology Research Investigational Products Center

    Austin, Texas, 78705, United States

  • United States Oncology Regulatory Affairs Corporate Office

    Austin, Texas, 78705, United States

  • Universitatsklinikum Tubingen

    Tübingen, 72076, Germany

  • University General Hospital of Evros-Alexandroupolis District

    Alexandroupoli, 68100, Greece

  • University Hospital of Ioannina

    Ioannina, 45500, Greece

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35249, United States

  • Universitätsklinikum Münster

    Münster, 48149, Germany

  • Vejle Sygehus

    Vejle, 7100, Denmark

  • Yale Cancer Center

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

RELAPSED OR REFRACTORY MULTIPLE MYELOMA